Buy DeschloroKetamine (DCK)

Product Overview

Deschloroketamine (DCK, 2-Phenyl-2-(methylamino)cyclohexan-1-one, CAS 4631-27-0) supplies researchers with a high-purity deschlorinated arylcyclohexylamine reference standard for NMDA receptor antagonist pharmacology research, dissociative compound SAR studies, and forensic toxicology analytical method development within controlled laboratory environments. Researchers looking to buy deschloroketamine for laboratory applications will find UltraRawz’s HPLC-verified material suitable for NMDA receptor subunit binding affinity profiling, comparative arylcyclohexylamine metabolic stability research, LC-MS/MS method development for deschlorinated dissociative detection in biological matrices, and sigma receptor interaction studies. DCK is the deschlorinated analogue of ketamine — the absence of the 2-chloro substituent on the phenyl ring removes the characteristic chlorine isotope doublet from MS spectra, provides a distinct HPLC retention profile, and alters receptor binding characteristics in ways documented in published comparative arylcyclohexylamine pharmacology literature. For research use only. Not for human or veterinary use. Not for clinical, diagnostic, or consumptive applications.

Deschloroketamine (O-PCM, 2-Phenyl-2-(methylamino)cyclohexanone) represents the simplest member of the arylcyclohexylamine dissociative compound class that retains NMDA receptor activity — making it a foundational reference compound for SAR studies examining the contribution of phenyl ring halogenation to arylcyclohexylamine receptor pharmacology. The removal of the 2-chloro substituent reduces molecular weight by approximately 34 Da (ketamine MW 237.73 vs DCK MW 203.28 g/mol) and eliminates the chlorine isotope doublet from GC-MS and LC-MS spectra, providing an analytically clean molecular ion at m/z 203 that aids method development for multi-compound dissociative screening panels. Published forensic toxicology case reports from European and North American jurisdictions have documented DCK in biological and seized material samples since 2015, establishing ongoing demand for authenticated reference standards. Buy deschloroketamine research material at UltraRawz for worldwide laboratory delivery with discreet packaging.

DCK research compound is available at ultrarawz.com/shop in powder and pellet formats across multiple quantities. Each batch is HPLC-verified at ≥98% purity with batch-specific COA. Related dissociative arylcyclohexylamine research compounds at UltraRawz include 2F-Ketamine (2-FDCK), O-PCE (2-oxo-PCE), DMXE, MXE, 3-MeO-PCP, and 3-MeO-PCE — browse at ultrarawz.com — Dissociatives.

Chemical Identity & Classification

Deschloroketamine carries CAS number 4631-27-0, molecular formula C₁₃H₁₇NO, and molecular weight 203.28 g/mol. Systematic IUPAC designation: 2-(methylamino)-1-phenylcyclohexan-1-one. Laboratory synonyms: DCK, O-PCM (2-oxo-PCM), deschloroketamine, 2-phenyl-2-(methylamino)cyclohexanone. Structural classification: arylcyclohexylamine — cyclohexanone scaffold with unsubstituted phenyl and N-methyl secondary amine at C-2 alpha position. Comparison with ketamine (2-chlorophenyl) and 2F-ketamine (2-fluorophenyl): DCK has an unsubstituted phenyl ring, eliminating halogen MS signatures and producing the lowest logP of the three compounds. Compound exists as a racemic mixture of R and S enantiomers at the C-2 chiral center. Protonated molecular ion [M+H]⁺: m/z 204. No halogen isotope doublet — single clean molecular ion. PubChem CID: 87397.

Chemical & Physical Characteristics

DCK manifests as white to off-white crystalline powder (HCl salt or free base). HCl salt melting point: ~220–224°C. DMSO solubility: ≥10 mg/mL. Methanol and ethanol: freely soluble. Aqueous solubility: moderate (HCl salt better than free base). logP: ~1.8 (calculated, free base — lower than ketamine ~2.2, reflecting absence of 2-chloro substituent). UV absorption: ~250–260 nm (phenyl chromophore without halogen perturbation). The absence of ring halogenation compared to ketamine and 2-FDCK produces a characteristically different HPLC retention time and MS/MS fragmentation pattern — the simplest arylcyclohexylamine fragmentation series, useful as a reference fragmentation template for predicting ring-substituted analogue fragment series. Hygroscopicity: moderate (HCl salt). Racemic — enantiomeric separation possible on chiral HPLC for stereoselective pharmacological research.

Purity & Analytical Verification

Production lots certify ≥98% purity by gradient HPLC (C18 reverse-phase, acetonitrile/0.1% formic acid gradient, UV 254 nm, area normalization). Identity confirmed by: ¹H NMR (CDCl₃) — unsubstituted phenyl ring aromatic protons as multiplet at δ 7.2–7.5 ppm (5H, distinguishing from 2-chlorophenyl pattern of ketamine with 4 aromatic H and different coupling constants, and 2-fluorophenyl pattern of 2-FDCK with F-H coupling). GC-MS: molecular ion m/z 203 (single peak, no halogen isotope doublet — distinguishes from ketamine m/z 237/239 doublet and 2-FDCK m/z 219 single). LC-MS/MS: [M+H]⁺ m/z 204; fragments m/z 186 (loss of H₂O), m/z 147 (loss of methylamine + H₂O), m/z 105 (benzoyl cation, phenyl + CO). Karl Fischer water content: <1.0% w/w. COA at support@ultrarawz.com.

Quality Control & Batch Integrity

Each production batch undergoes multi-stage quality verification: HPLC purity assessment, ¹H NMR identity confirmation (phenyl ring proton count and pattern verification — 5H unsubstituted vs 4H halogenated patterns), GC-MS single molecular ion confirmation (absence of isotope doublet verified as negative identity criterion for halogen contamination), Karl Fischer water content, and visual appearance inspection. Batch-specific lot numbers enable full traceability. Retained reference samples support stability monitoring and reanalysis. Inter-batch consistency verified via NMR overlay and HPLC retention time comparison.

Safety, Handling & Laboratory Precautions

Handle exclusively within a properly ventilated fume hood. Required PPE: nitrile gloves (double-glove), lab coat, safety glasses, N95 respirator when handling powder. NMDA receptor antagonist — prevent dermal absorption; verify glove integrity. Anti-static weighing vessels recommended. Note: racemic mixture — researchers requiring enantioselective data should use chiral HPLC separation prior to pharmacological assay work. Spill: absorb with inert material, sealed container, institutional chemical waste disposal. Emergency: skin contact — wash with soap and water; eye contact — flush 15 minutes, seek medical attention. Compound usage log maintained per lot for research documentation.

Packaging, Labeling & Storage

DCK research compound is supplied in sealed amber glass vials with inert closures and desiccant packs, in discreet external packaging. Labels specify compound name, CAS 4631-27-0, lot number, purity, and research use notice. Recommended storage: -20°C long-term; ≤25°C short-term (active use, max 2 weeks, desiccated, sealed). Amber glass protects against UV photodegradation. Do not store in polystyrene. Under recommended conditions, compound integrity maintained for lot expiry period on COA.

Intended Research Use & Market Positioning

DCK research compound is positioned for: NMDA receptor pharmacology programs examining phenyl ring substitution effects on arylcyclohexylamine receptor binding affinity — DCK as the unsubstituted reference point for comparing chloro (ketamine), fluoro (2-FDCK), and methoxy (MXE) phenyl ring substitution effects; forensic toxicology laboratories developing LC-MS/MS identification methods for DCK in biological and seized material matrices; metabolic stability research comparing Phase I biotransformation pathways of halogenated versus non-halogenated arylcyclohexylamine analogues using HLM preparations; sigma receptor binding studies examining DCK’s sigma-1 and sigma-2 interaction profile relative to ring-substituted analogues; and academic dissociative pharmacology programs building comprehensive arylcyclohexylamine SAR datasets. Browse related compounds at ultrarawz.com — Dissociatives.

Ordering, Availability & Fulfillment

DCK is available in powder and pellet formats across multiple quantities — see variants above for current pricing. Payment methods: Bitcoin (BTC), bank transfer, Interac E-Transfer (Canada), Apple Pay (US), Zelle (US), Chime (US), Revolut (Europe), gift cards — full details at ultrarawz.com/payment. Orders processed same day, discreet secure packaging. Worldwide shipping from US and Netherlands warehouses. Delivery: 2–5 business days (US/EU); 5–10 days international. Institutional pricing and COA requests: support@ultrarawz.com or WhatsApp +1 (567) 457-7456. Track at ultrarawz.com/track-order.

Legal & Regulatory Disclaimer

Deschloroketamine (CAS 4631-27-0) is supplied strictly for laboratory research purposes only. Not for human or veterinary use. Not for clinical, diagnostic, or consumptive applications. Regulatory status varies by jurisdiction — DCK is controlled in several countries and US states. Purchasers are solely responsible for verifying compliance with all applicable regulations prior to ordering. UltraRawz supplies exclusively to qualified research professionals for legitimate laboratory research.

Frequently Asked Questions

Q: What is the key structural difference between DCK and ketamine?
A: DCK has an unsubstituted phenyl ring; ketamine has a 2-chlorophenyl ring. This single difference reduces MW by 34 Da (203 vs 237), eliminates the chlorine isotope doublet from MS spectra, reduces logP (lower lipophilicity), and alters phenyl ring electronic density — producing measurable differences in NMDA receptor binding kinetics in published comparative pharmacology literature.

Q: How does the GC-MS spectrum distinguish DCK from ketamine?
A: DCK molecular ion appears at m/z 203 as a single peak. Ketamine shows a ⁷⁹Cl/⁸¹Cl isotope doublet at m/z 237/239 (~3:1 ratio). The absence of an isotope doublet in DCK spectra is an immediate visual distinguishing feature in full-scan GC-MS library searching.

Q: What purity does UltraRawz DCK achieve?
A: ≥98% by HPLC area normalization. COA with HPLC chromatogram and NMR data available on request.

Q: Is DCK supplied as a racemate or single enantiomer?
A: Racemate (R and S enantiomers). Enantiomeric separation possible on chiral HPLC for researchers requiring stereoselective pharmacological data.

Q: What related dissociatives does UltraRawz carry?
A: 2F-Ketamine, O-PCE, DMXE, MXE, 3-MeO-PCP, 3-MeO-PCE, Methoxpropamine. Browse at ultrarawz.com — Dissociatives.

Q: Do you ship internationally?
A: Yes, worldwide from US and Netherlands. Purchasers must verify local regulations. See shipping & delivery.

Q: Is a COA available before purchasing?
A: Yes. Contact support@ultrarawz.com to request current lot COA documentation.