Buy 2F-Ketamine Spray – 25%

Product Overview

2F-Ketamine Spray – 25% contains 2-fluorodeschloroketamine (2-FDCK), systematically 2-(2-fluorophenyl)-2-(methylamino)cyclohexan-1-one, positioned as a high-purity arylcyclohexylamine reagent for advanced method validation, reference standard delivery, and quantitative analysis in professional laboratories. This fluorinated dissociative analog facilitates consistent chromatographic profiling and spectrometric characterization within validated research protocols. Formulated at 25% w/v (250 mg/mL) in research-grade solvent-propellant system meeting ≥98% active purity, the metered spray ensures uniform deposition for LC-MS calibration and extraction recovery studies.

Exclusively distributed for laboratory research, this calibrated spray receives no pharmaceutical formulation, stability qualification, or regulatory positioning beyond analytical reference applications. The precision actuator enables reproducible 10-50 μL aliquots ideal for quantitative surface standards and matrix-matched calibrators in controlled analytical workflows. For research use only. Not for human or veterinary use. Not for clinical, diagnostic, or consumptive applications.

Chemical Identity & Classification

2F-Ketamine (2-FDCK) is designated 2-(2-fluorophenyl)-2-(methylamino)cyclohexanone hydrochloride, IUPAC synonyms: 2′-fluoro-2-oxo-N-methylcyclohexanamine, with CAS 111982-49-1 (HCl salt). Classified as arylcyclohexylamine dissociative (deschloro-ketamine ortho-fluoro analog), functions as certified analytical reference material.

Molecular formula C13H16FNO- HCl (MW 257.73 g/mol); InChI=1S/C13H16FNO.ClH/c1-15-13(9-5-4-8-12(13)16)11-7-3-2-6-10(11)14/h2-3,6-7,15H,4-5,8-9H2,1H3;1H; SMILES CNC1(CCCC1=O)c2ccccc2F.Cl characteristic fragments: m/z 222 [M+H]+, 204 [M+H-CH3NH2]+, 179 [fluoroaniline]+.​

Chemical & Physical Characteristics

25% spray formulation appears as clear, colorless pressurized solution with metered valve delivering 25-50 μL uniform droplets (Dv50 35 μm, laser diffraction). Aerosol plume optimized for quantitative deposition onto swabs, disks, or 96-well plates without satellite droplets.

Active solubility >250 mg/mL in ethanol/isopropanol carrier; complete chromatographic compatibility with C18, HILIC, and chiral columns; spray solvent evaporates <30s leaving pure crystalline residue. Stability: 24 months at 15-25°C pressurized; avoid >40°C or puncture.​

Purity & Analytical Verification

≥98% purity specification exceeds forensic reference standards (USP <621> HPLC ≥99.0% typical); orthogonal confirmation: LC-DAD 220 nm (98.5-101.5% w/w), GC-FID (RRT 1.12 vs ketamine), 1H-NMR (DMSO-d6: δ 7.65-7.20 m 4H aromatic, 2.35 s 3H N-CH3).​

Batch QC includes aerosol content uniformity (RSD <2.0%, n=10), droplet size distribution (Span <1.2), spray weight/actuation (CV <3%), and active assay vs external std (HPLC, 24.5-25.5% w/v). COAs provide plume geometry plots and matrix factor data.​

Quality Control & Batch Integrity

Production under ISO 17025-equivalent controls: in-process actuator function (leak rate <0.1 μL/day), fill weight gravimetric verification (±1.0% target), pressure integrity (11-13 bar N2), and microbial testing (USP <61>/<62>). Lot traceability from API synthesis through crimping date coding.​

Three-point release: potency (HPLC ext std), delivery (gravimetric n=20), purity (orthogonal), heavy metals (ICP-MS <10 ppm Pb), residual solvents (HS-GC ICH Q3C).​

Safety, Handling & Laboratory Precautions

Aerosol handling requires Type A1 fume hood (vapor capture >99%); PPE: fluoropolymer gloves (Viton®), full-face shield, nitrile apron per solvent vapor ACGIH TLVs. Secondary containment tray prevents canister tip-over; spark-free environment (ATEX Zone 2).

Pressurized container waste: depressurize under hood into liquid N2 trap, then RCRA D001/D003 incineration; no venting to atmosphere permitted.​

Packaging, Labeling & Storage

30mL aluminum MDC (metered dose container) with 100-200 actuations, child-resistant actuator, dust cap; tamper-evident overwrap with 2D barcode lot coding. GHS labels: “UN1950 Class 2.1, Research Chemical 25% w/v, Keep Away from Heat.”​

Store 15-25°C upright; 24-month expiry when punctures intact; excursion 2-8°C permitted.​

Intended Research Use & Market Positioning

25% spray concentration optimizes quantitative toxicology (cutoff calibrators 10-500 ng/mL), extraction efficiency studies (spray-to-swab recovery >95%), and dried matrix spot (DMS) preparation for LC-MS/MS PK analysis. Precision aerosol eliminates volumetric pipetting error (CV <1% vs 5-10% manual).​

Laboratory research reagent exclusively; no clinical trial, veterinary, or therapeutic positioning. For research use only. Not for human or veterinary use. Not for clinical, diagnostic, or consumptive applications.

Ordering, Availability & Fulfillment

Qualified institutional procurement via WooCommerce with IATA 2.2/UN1950 documentation; bulk laboratory pricing tiers available. 2-8°C shipping with thermal data loggers; 48-hour ambient stability certified.​

Technical support supplies validated LC-MS methods (MRM transitions, IS options) and spray pattern characterization data.​

Legal & Regulatory Disclaimer

2F-Ketamine Spray – 25% constitutes unregistered laboratory research formulation absent FDA/EMA/EMA authorization for human investigational use, veterinary application, or commercial distribution. Diversion to administration routes, therapeutic contexts, or clinical research expressly prohibited; no GLP tox data, ADME profiles, or human safety information provided beyond analytical specifications. For research use only. Not for human or veterinary use. Not for clinical, diagnostic, or consumptive applications.

Purchasers certify DEA Schedule I research authorization, institutional IBC registration, and complete jurisdictional compliance for possession, analysis, and disposition.​