Buy Fluoroexetamine (FXE) Crystal

Product Overview

Fluoroexetamine (FXE) Crystal delivers a brandless, high-purity (≥98%) arylcyclohexylamine compound, systematically named 2-(ethylamino)-2-(3-fluorophenyl)cyclohexan-1-one, designed exclusively for laboratory and analytical research. Identified by CAS 855350-44-6, this 3′-fluoro substituted analog serves as a specialized reference standard for forensic toxicology panels, structural characterization, and method validation in professional research settings. The crystalline form ensures uniformity, accurate subsampling, and long-term stability, facilitating reliable integration into LC-MS, GC-MS, and NMR workflows. For research use only. Not for human or veterinary use. Not for clinical, diagnostic, or consumptive applications.

Qualified laboratories employ FXE Crystal for calibration of novel psychoactive substance detection methods, impurity profiling of fluorinated cyclohexanone derivatives, and library expansion in non-clinical analytical programs. Batch-controlled production from verified precursors guarantees reproducibility across studies requiring precise chemical standards.

Chemical Identity & Classification

Fluoroexetamine carries CAS 855350-44-6 (hydrochloride salt), with free base formula C14H18FNO and molecular weight 235.30 g/mol (271.76 g/mol HCl salt). IUPAC name 2-(ethylamino)-2-(3-fluorophenyl)cyclohexan-1-one includes synonyms 3′-Fluoro-2-oxo-PCE, 3-FXE, and Fluorexetamine hydrochloride. InChI=1S/C14H18FNO/c1-2-16-14(9-4-3-8-13(14)17)11-6-5-7-12(15)10-11/h5-7,10,16H,2-4,8-9H2,1H3 and InChIKey (from PubChem CID 137332183) enable exact matching. Classified as an analytical reagent and arylcyclohexylamine reference standard for research use.

Meta-fluoro positioning distinguishes from 2-FXE isomers via chromatographic retention and MS fragmentation (characteristic m/z 174, 109), critical for forensic differentiation.

Chemical & Physical Characteristics

FXE Crystal appears as a white to off-white crystalline solid with defined melting point ~140-143°C, suitable for thermal analysis and formulation stability. Solubility profiles indicate good performance in DMSO (~15 mg/mL), ethanol (~10 mg/mL), and moderate in PBS pH 7.2 (~2 mg/mL), aligned with XLogP3-AA ~2.9 and TPSA 38.3 Ų. Density ~1.2 g/cm³ supports precise gravimetric handling without clumping.

Low volatility, UV λmax ~260 nm (fluorophenyl influence), and exact mass 235.1372 Da enable robust HPLC/HRMS detection. Crystalline lattice minimizes moisture uptake, preserving integrity during ambient storage and dissolution protocols.

Purity & Analytical Verification

Batches of Fluoroexetamine (FXE) Crystal exceed ≥98% purity, confirmed orthogonally by HPLC (C18, 254 nm >98.5% area), GC-MS (EI full scan), ¹H-NMR (CDCl3: ethyl CH3 triplet 1.12 ppm, CH2 quartet 3.35 ppm, fluoro-Ar H shifts), ¹³C-NMR, and LC-QTOF-MS ([M+H]⁺ 236.1449 ±5 ppm). Related substances <0.3%, residual solvents <3000 ppm (ICH Q3C), heavy metals <10 ppm ICP-OES.

Comprehensive COAs supply overlaid chromatograms, spectral libraries vs. certified material (Cayman Chemical batch 0625438-1), KF water (<0.4%), verifying quantitative fitness for method accreditation.​

Quality Control & Batch Integrity

Regiospecific synthesis couples 3-fluorophenyl Grignard with cyclohexanone, followed by ethylamine reductive amination, fractional recrystallization, and crystal growth optimization. Lot serialization traces ≥99.5% aryl halide precursors through final PSD control (D50 20-50 μm). Third-party verification includes FTIR (C-F 1230 cm⁻¹, C=O 1710 cm⁻¹), EA (C 65.1%, H 7.4%, N 5.1% HCl-adjusted), and chiral HPLC (racemic).

ICH Q1A stability under 40°C/75%RH retains >98% purity at 18 months; real-time data (25°C/60%RH) supports 36-month expiry with retention sampling.​

Safety, Handling & Laboratory Precautions

Process FXE Crystal in Class I/II fume hoods with full PPE: 15 mil nitrile gloves, chemical splash goggles, Tyvek labwear. Enclosed analytical balances and anti-static spatulas limit aerosol to <20 μg/m³. Incompatible with strong oxidizers, bases, Lewis acids.

GHS classifies H315/H319/H335 irritant; spill protocol employs vermiculite absorption, 5% NaHCO3 neutralization, incineration as RCRA U-list waste. Personnel training required per OSHA 1910.1450.​

Packaging, Labeling & Storage

Supplied in amber borosilicate vials (13-100 mm, PTFE-lined septa, crimped seals) with secondary foil pouches and molecular sieves. Labels conform to GHS/CLP (CAS 855350-44-6, ≥98%, P261/P264/P280), scannable QR to digital COA/spectra. Tamper-evident bands secure chain-of-custody.

Store desiccated at -20°C shielded from light; avoid freeze-thaw. Accelerated studies project >95% retention through validated shelf-life.​

Intended Research Use & Market Positioning

FXE Crystal calibrates forensic NPS screens (serum/plasma LODs 1-10 ng/mL), supports R&D of fluorinated arylcyclohexylamine SAR, and validates methoxetamine analog detection via LC-QTOF libraries. Toxicology labs employ for confirmation against ketamine metabolites.

3′-fluoro specificity addresses isomer misidentification risks (vs. 2-FXE), positioning as premium ISO 17025 reference over uncharacterized material.​

Ordering, Availability & Fulfillment

WooCommerce maintains active lots with 256-bit SSL/3DS, real-time stock visibility. Same-day fulfillment ships insulated (UN 3077, research chemical) via carriers with signature/track. Volume tiers, custom COA extracts streamline procurement.​

Support portal enables batch lookup, SDS/COA instant download, compliance attestation.​

Legal & Regulatory Disclaimer

Fluoroexetamine (FXE) Crystal sold strictly for research purposes only, not for human or veterinary use, clinical, diagnostic, or therapeutic applications. Purchasers verify all jurisdictional regulations for arylcyclohexylamine research chemicals. For research use only. Not for human or veterinary use. Not for clinical, diagnostic, or consumptive applications.