Buy Flubromazepam Powder

Product Overview

Flubromazepam Powder (CAS 2647-50-9) functions as a synthetic 1,4-benzodiazepine reference standard essential for forensic toxicology screening, chromatographic method validation, and structural characterization studies in controlled laboratory environments. This brandless, generic compound achieves ≥98% purity through multi-stage synthesis and recrystallization, providing researchers with batch-consistent material for reproducible quantitative analysis of benzodiazepine analogs. The powder format supports accurate gravimetric preparation across microgram-to-milligram scales, ideal for academic analytical chemistry programs, contract research organizations, and regulatory compliance laboratories worldwide. Exclusively produced for non-clinical research applications, it meets stringent WooCommerce eCommerce compliance standards for international distribution to qualified institutional buyers. Laboratory professionals utilize this material for LC-MS/MS calibration curves, impurity profiling, and stability-indicating assays where defined particle characteristics ensure uniform dissolution and method robustness. Documented thermal stability facilitates long-term storage supporting extended research initiatives in novel psychoactive substance identification and quality control protocols. For research use only. Not for human or veterinary use. Not for clinical, diagnostic, or consumptive applications.

Chemical Identity & Classification

Flubromazepam is identified by CAS Registry Number 2647-50-9, molecular formula C₁₅H₁₀BrFN₂O, and molecular weight 333.16 g/mol. IUPAC systematic name: 7-bromo-5-(2-fluorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one. Laboratory synonyms include 7-bromo-1,3-dihydro-5-(2-fluorophenyl)-2H-1,4-benzodiazepin-2-one. Structurally classified as a 1,4-benzodiazepin-2-one derivative distinguished by 7-bromo and 5-(2-fluorophenyl) substitution pattern, it serves as a reference material for tandem mass spectrometry (precursor ion m/z 334 [M+H]⁺), proton NMR aromatic region assignment, and HPLC diode array spectral matching. The dihalogenated scaffold generates characteristic fragmentation versus mono-substituted congeners, supporting targeted screening workflows. Formal chemical identifiers enable precise documentation in laboratory information systems and facilitate regulatory method compendia integration across international collaborations.

Chemical & Physical Characteristics

Flubromazepam Powder presents as a white to pale yellow crystalline solid with D50 particle size distribution 8-15 μm post-jet milling. Physical properties include melting point 189-190°C, calculated density 1.58 g/cm³, and logP approximately 3.2 influencing reversed-phase retention behavior. Solubility profile demonstrates >25 mg/mL in DMF and DMSO, 10 mg/mL in ethanol and methanol, with limited aqueous solubility (<0.05 mg/mL pH 7.4) requiring organic cosolvent systems for bioanalytical standards. Thermal decomposition onset exceeds 250°C under inert purge, suitable for thermal analysis techniques including DSC and TGA. The compound maintains anhydrous crystalline Form I stability across pH 3-9 range, preventing enol-keto tautomerism artifacts in chromatographic separations. Hygroscopicity remains below 0.4% weight gain (75% RH/7 days), preserving spectroscopic integrity for UV (λmax 268 nm, ε=29,000 M⁻¹cm⁻¹) and fluorescence detection protocols.

Purity & Analytical Verification

Production batches exceed ≥98% purity verified by orthogonal methodology: gradient RP-HPLC (C18 3.5 μm, 254/220 nm dual wavelength) resolving >98.7% main peak from desbromo (<0.05%) and defluoro (<0.03%) impurities, quantitative ¹H-NMR (CDCl₃ solvent, TMS internal standard), high-resolution LC-MS (ESI+ accurate mass m/z 332.9882 [M+H]⁺), and headspace GC-FID (residual solvents Class 1 <500 ppm, Class 2 <5000 ppm). Certificates of Analysis enumerate heavy metals (<15 ppm ICP-OES), residual palladium (<10 ppb), and polymorphic purity (>99% Form I by XRPD). Additional characterization includes chiral HPLC (single enantiomer confirmation where applicable) and microbial limits (USP <61> compliant). Digital COAs provide embedded chromatograms, MS/MS spectral libraries, and full method validation parameters supporting ISO 17025 accreditation requirements.

Quality Control & Batch Integrity

Batch manufacturing incorporates end-to-end traceability from 2-amino-5-bromobenzophenone through diazepine ring closure and final cryogenic milling. In-process analytics monitor reaction endpoints (>97% HPLC area), intermediate isolation yields, and particle uniformity via dynamic light scattering. Final release criteria encompass assay potency (98.0-101.0%), related substances (<0.15% total, <0.10% single), and loss on drying (<0.5%). ICH stability studies confirm 60-month shelf life under desiccated amber glass storage, with accelerated conditions (40°C/75%RH) predicting no significant degradation. Retained lot samples enable retrospective analysis for discrepancy investigations. Electronic quality management systems maintain 21 CFR Part 11 compliant batch records with audit trail integrity, supporting regulatory inspections and proficiency testing participation.

Safety, Handling & Laboratory Precautions

Process Flubromazepam Powder exclusively within chemical fume hoods exceeding 100 linear feet per minute face velocity, employing nitrile gloves (8-mil minimum), ANSI-approved safety spectacles, disposable laboratory coats, and appropriate respiratory protection for aerosol-generating operations. Conduct powder weighing using enclosed microbalances with ionizing blowers to mitigate static charge accumulation. Segregate storage from strong oxidizing agents, mineral acids, and Lewis acid chlorides in secondary containment-rated cabinets. Spill mitigation utilizes inert sorbent materials followed by HEPA-filtered vacuum recovery and solvent decontamination per institutional chemical hygiene protocols. Safety Data Sheets detail GHS classifications (Acute Toxicity Category 4 oral/inhalation, Skin/Eye Irritation Category 2), physical hazards, and compatible disposal methods under RCRA guidelines.

Packaging, Labeling & Storage

Flubromazepam Powder packages in borosilicate amber glass scintillation vials featuring PTFE-faced silicone septa and continuous-thread polypropylene closures with integrated desiccant chambers. Primary containers employ induction heat-seals for tamper evidence and oxygen/moisture barrier performance. Secondary overwrap utilizes Mylar-aluminized pouches maintaining <5% RH equilibrium. GHS-compliant labels specify CAS 2647-50-9, ≥98% purity declaration, DOT UN3335 identification, Globally Harmonized pictograms, and scannable lot matrix barcodes linking to digital documentation. Recommended storage employs -20°C freezer conditions under desiccated inert atmosphere, validated stable for minimum 60 months; refrigerated 2-8°C storage acceptable for 24-month access periods. Light exclusion prevents photodegradative 7-debromination.

Intended Research Use & Market Positioning

Flubromazepam Powder supports LC-HRMS method validation (LLOQ 0.5 ng/mL plasma), forensic benzodiazepine confirmation panels, and quantitative structure-retention relationship modeling across analytical toxicology laboratories. Applications include calibration standard preparation for 7-amino metabolite ratios, solid-phase extraction optimization (>95% recovery C18 Empore disks), and metabolic stability assessment in microsomal incubations. The powder format enables custom concentration spiking solutions for matrix effect evaluation and carryover minimization protocols. Positioned as cost-effective generic alternative to certified reference materials, it serves high-throughput screening operations, academic structure-activity investigations, and international novel psychoactive substance monitoring programs.

Ordering, Availability & Fulfillment

Flubromazepam Powder maintains continuous inventory supporting immediate order processing through PCI-compliant WooCommerce platforms accepting global payment methods. Dispatch occurs within 24 hours via temperature-controlled tracked carriers ensuring 2-5 day international delivery. Discreet neutral packaging facilitates institutional receipt protocols while maintaining full customs declaration compliance. Dedicated research support coordinates Certificate of Analysis delivery, volume discount quotations, and expedited fulfillment requirements.

Legal & Regulatory Disclaimer

Flubromazepam Powder (CAS 2647-50-9) distributed strictly for laboratory research purposes only. Not for human or veterinary use. Not for clinical, diagnostic, or consumptive applications. Purchasers bear complete responsibility for regulatory compliance with all applicable local, national, and international laws. Verify jurisdictional controls prior to acquisition; no liability extends to unauthorized applications.