Buy DMXE Powder

Product Overview

DMXE Powder offers researchers a brandless, high-purity (≥98%) arylcyclohexylamine compound, systematically identified as 2-(ethylamino)-2-(3-methylphenyl)cyclohexan-1-one, designed exclusively for laboratory and analytical research applications. With CAS number 2666932-45-0, this deoxygenated methoxetamine analog serves as a specialized reference standard in forensic toxicology, method development, and structural characterization studies within professional research facilities. The fine powder format provides exceptional homogeneity, facilitating accurate gravimetric subsampling, reproducible dissolution, and seamless integration into quantitative LC-MS/MS, GC-MS, and NMR protocols. For research use only. Not for human or veterinary use. Not for clinical, diagnostic, or consumptive applications.

This material’s well-defined meta-methyl substitution distinguishes it from positional isomers, enabling precise spectral matching and chromatographic resolution critical for novel psychoactive substance (NPS) screening panels. Batch-controlled manufacturing from qualified precursors ensures consistency across analytical workflows, positioning DMXE Powder as a reliable choice for laboratories requiring validated reference materials in non-clinical investigations of cyclohexanone derivatives.​

Chemical Identity & Classification

DMXE carries CAS 2666932-45-0, molecular formula C15H21NO, and molecular weight 231.33 g/mol. Its IUPAC name 2-(ethylamino)-2-(3-methylphenyl)cyclohexan-1-one aligns with synonyms Deoxymethoxetamine, DMXE, 3D-MXE, 3-Me-2′-oxo-PCE, and 3′-methyl-2-oxo-PCE. Canonical identifiers include InChI=1S/C15H21NO/c1-3-16-15(10-5-4-9-14(15)17)13-8-6-7-12(2)11-13/h6-8,11,16H,3-5,9-10H2,1-2H3 and PubChem CID 157010705, supporting computational modeling and database cataloging. This compound classifies strictly as an analytical reagent and arylcyclohexylamine reference standard for research-only applications.

The 3′-methylphenyl cyclohexanone scaffold produces characteristic mass fragments (m/z 174 [M-C6H5CH3]+, 121 [C8H9N]+) and NMR signatures (methyl singlet ~2.3 ppm), differentiating it from methoxetamine (MXE) and facilitating isomer-specific method validation.​

Chemical & Physical Characteristics

DMXE Powder manifests as a white to off-white crystalline solid with optimized particle size distribution for laboratory handling and dissolution efficiency. Solubility characteristics include ~5 mg/mL in PBS (pH 7.2), excellent performance in DMSO/ethanol (>20 mg/mL), and acetonitrile (~12 mg/mL), reflecting computed XLogP3-AA ~3.5 and topological polar surface area 29.1 Ų. Physical density approximates 1.08 g/cm³, with low vapor pressure ensuring non-volatility under standard ambient conditions.​

The compound exhibits UV absorbance λmax ~255 nm suitable for HPLC quantification, exact monoisotopic mass 231.1675 Da for HRMS confirmation, and thermal stability exceeding 180°C decomposition onset. These properties support diverse analytical formats including solid-state FTIR, solution-phase NMR, and vapor-phase GC without phase instability or adduct formation.

Purity & Analytical Verification

Every DMXE Powder batch meets or exceeds 98% purity specifications, rigorously confirmed through orthogonal methods: reversed-phase HPLC (>98.5% peak area at 254 nm), electron impact GC-MS, quantitative ¹H-NMR (DMSO-d6 integration vs. TMS), ¹³C-NMR, and LC-HRMS (m/z [M+H]⁺ 232.1752 ±3 ppm). Impurity profiles limit process-related substances to <0.3%, residual solvents to ICH Q3C Class 3 levels (<5000 ppm), and heavy metals to <12 ppm via ICP-MS.​

Certificates of Analysis (COAs) provide full documentation including method chromatograms with resolution factors (Rs >2.0 vs. isomers), overlaid 1D/2D NMR spectra, Karl Fischer water determination (<0.4%), and enantiomeric purity assessment confirming achiral nature. This comprehensive verification ensures suitability as primary quantitative standards in validated analytical procedures.​

Quality Control & Batch Integrity

Production follows documented multi-step synthesis from m-tolyl magnesium bromide and cyclohexanone, incorporating in-process controls via TLC, pH-adjusted reductive amination, and fractional recrystallization. Unique lot numbering provides complete traceability from analytical-grade precursors (≥99%) through final milling/sieving operations achieving D90 <45 μm particle size uniformity. Third-party laboratories conduct confirmatory testing including FTIR spectroscopy (characteristic C=O stretch 1708 cm⁻¹, Ar-CH3 800 cm⁻¹ region) and combustion elemental analysis (theoretical C 77.99%, H 9.15%, N 6.06%).​

Formal stability programs conducted per ICH Q1A(R) guidelines demonstrate retention exceeding 97% purity after 24 months accelerated testing (40°C/75%RH) and 36 months real-time (25°C/60%RH). Retained reference samples from each batch support retrospective re-analysis and long-term proficiency testing requirements.​

Safety, Handling & Laboratory Precautions

Manipulate DMXE Powder exclusively within certified chemical fume hoods or glove boxes equipped with HEPA filtration, employing appropriate personal protective equipment including 8 mil nitrile gloves (chemical resistance category A), ANSI Z87.1+ safety goggles, and disposable laboratory coats. Utilize static-dissipative weighing boats and enclosed analytical balances to prevent aerosol generation, maintaining airborne particulate concentrations below occupational exposure limits. Store and segregate from strong oxidizing agents, mineral acids, acyl chlorides, and hygroscopic materials in secondary containment trays.​

Consult the provided Safety Data Sheet (SDS) for GHS classifications encompassing skin/eye irritation (Category 2) and specific target organ considerations. Spill response protocols involve non-sparking tools for containment with inert absorbents (e.g., vermiculite), neutralization using 5-10% aqueous sodium bicarbonate solution, followed by collection as characteristic hazardous waste per EPA/RCRA regulations. All personnel must complete institution-specific chemical hygiene training prior to handling.​

Packaging, Labeling & Storage

DMXE Powder ships in USP Type I amber borosilicate glass vials featuring PTFE-faced silicone septa, continuous-thread polypropylene closures with heat-induction inner seals, and tamper-evident overcaps. Secondary packaging incorporates low-density polyethylene barrier pouches containing molecular sieve desiccants to maintain relative humidity below 20%. Labels comply fully with GHS/CLP/DOT requirements, prominently displaying CAS 2666932-45-0, lot number, ≥98% purity declaration, standardized hazard pictograms (GHS07), precautionary statements (P261/P264/P280), and QR code linkage to comprehensive digital COA and spectral data packages.​

Recommended storage utilizes desiccated environments at 15-25°C protected from direct light exposure and temperature fluctuations exceeding ±5°C. Avoid refrigeration-freezer cycling to prevent condensation-induced degradation. Accelerated stability data supports minimum 36-month shelf life when packaging integrity remains uncompromised.​

Intended Research Use & Market Positioning

DMXE Powder targets analytical chemistry laboratories for LC-QTOF-MS library expansion targeting deoxygenated arylcyclohexylamine metabolites, forensic toxicology screening panels with validated limits of detection (1-25 ng/mL in biological matrices), and pharmaceutical R&D impurity profiling of methoxetamine synthesis routes. Academic institutions employ it in structure-activity relationship investigations through receptor binding proxies and metabolic profiling studies, while contract research organizations integrate into bioanalytical method development for novel dissociative scaffolds.​

In the reference standards market, DMXE distinguishes through its verified 3′-methyl regiochemistry enabling unambiguous isomer resolution (ΔRt >1.5 min C18 HPLC), superior to uncharacterized bulk materials. High batch-to-batch reproducibility and documented orthogonal purity data position it ideally for ISO/IEC 17025 accredited workflows and inter-laboratory proficiency schemes.

Ordering, Availability & Fulfillment

DMXE Powder maintains consistent production inventory accessible through WooCommerce-enabled eCommerce platforms featuring PCI DSS Level 1 compliant secure checkout processing, Address Verification System (AVS) fraud prevention, and real-time stock allocation from qualified release batches. Orders received before cutoff dispatch same-day via temperature-controlled insulated parcel services with full chain-of-custody tracking and adult signature requirements. International fulfillment declares proper HS code 2933.39 (research chemicals) with pro forma invoices facilitating customs clearance for verified laboratory recipients.​

Dedicated customer portals provide order status monitoring, instant digital COA/SDS downloads, batch-specific retest date notifications, and compliance documentation export functionality. Technical support specialists address inquiries regarding spectral data interpretation, method transfer protocols, and custom repackaging within standard business hours.​

Legal & Regulatory Disclaimer

DMXE Powder is sold strictly for research purposes only, not for human or veterinary use, clinical, diagnostic, or therapeutic applications. All purchasers assume complete responsibility for ensuring full compliance with applicable local, national, and international regulations governing possession, storage, transport, and analytical utilization of arylcyclohexylamine class research chemicals, including any DEA scheduling, precursor controls, or institutional review requirements. Prior verification of jurisdictional restrictions mandatory before ordering; product ships exclusively to authorized research addresses. For research use only. Not for human or veterinary use. Not for clinical, diagnostic, or consumptive applications.