Buy 2F-Ketamine Pellets – 50mg

Product Overview

2F-Ketamine Pellets – 50mg contain 2-fluorodeschloroketamine (2-FDCK), systematically 2-(2-fluorophenyl)-2-(methylamino)cyclohexan-1-one, positioned as a high-purity dissociative research reagent for LC-MS calibration, reference standard preparation, and structural elucidation in professional analytical laboratories. This ortho-fluorinated ketamine analog (C13H16FNO, MW 221.27 g/mol) supports reproducible method development within validated arylcyclohexylamine research protocols. Each 50mg pellet utilizes micro-precision compression of ≥98% pure crystalline HCl salt with inert pharmaceutical-grade binders, ensuring complete dissolution and analytical consistency.

Exclusively manufactured for laboratory research applications, these pellets undergo no pharmaceutical qualification, bioburden testing, or regulatory clearance beyond analytical reference specifications. The compact 50mg discrete dosage facilitates direct quantitative transfer for low-concentration calibrators (1-100 ng/mL) in controlled environments adhering to institutional quality management systems. For research use only. Not for human or veterinary use. Not for clinical, diagnostic, or consumptive applications.

Chemical Identity & Classification

2F-Ketamine designates 2-(2-fluorophenyl)-2-(methylamino)cyclohexanone hydrochloride (CAS 111982-50-4 free base, 111982-49-1 HCl salt), IUPAC synonyms: 2′-fluoro-2-oxo-N-methyl-PCE, fluoroketamine. Classified within arylcyclohexylamine dissociatives as deschloro-ketamine with ortho-fluoro substitution replacing chlorine, functions exclusively as certified analytical reference material.

Characteristic identifiers: InChI=1S/C13H16FNO.ClH/c1-15-13(9-5-4-8-12(13)16)11-7-3-2-6-10(11)14/h2-3,6-7,15H,4-5,8-9H2,1H3;1H; SMILES CNC1(CCCC1=O)c2ccccc2F.Cl; MS fragments m/z 222 [M+H]+, 204 [M+H-NHCH3]+, 179 [C6H5FNHCH3]+. Hydrochloride salt predominates for enhanced solubility/stability in research applications.

Chemical & Physical Characteristics

50mg pellets manifest as uniform off-white compressed discs (3-4mm diameter, 2-3mm thickness) containing crystalline 2-FDCK HCl matrixed within mannitol/microcrystalline cellulose scaffold. Discrete unit dosage specification eliminates microgram weighing errors, supporting direct volumetric dissolution (complete <15 min sonication, methanol/water 1:1).

Solubility profile: >50 mg/mL methanol/acetonitrile; >25 mg/mL aqueous PBS pH 7.4; optimized for C18/HILIC chromatography without matrix effects >10%. Physical stability: hardness 3-5 kp, friability <0.8%, disintegration USP <701> <10 min; shelf life 24 months desiccated.

Purity & Analytical Verification

≥98% purity exceeds forensic reference standards (typical HPLC 99.2±0.3% auc 220nm); orthogonal characterization: LC-QTOF exact mass 222.1293 Da (error <2 ppm), GC-EI MS base peak m/z 179, 1H-NMR (DMSO-d6) diagnostic fluoro-aromatic 7.65-7.25 ppm (m, 4H), N-CH3 2.38 ppm (s).

Batch QC suite: content uniformity RSD <1.5% (n=20), chiral HPLC S-enantiomer >99%, residual solvents ICH Q3C (<5000 ppm ethanol), heavy metals ICP-MS <5 ppm Pb. COAs include dissolution profiles, particle size distribution (D90 <50 μm post-milling), and ketamine positional isomer discrimination data.​

Quality Control & Batch Integrity

Automated rotary compression maintains fill weight 50.0±0.8 mg (RSD 1.2%), monitored via NIR spectroscopy in-process; full lot genealogy from API synthesis (Grignard 2-fluorobenzonitrile + cyclopentylMgBr ring expansion) through packaging. ISO 17025-equivalent documentation satisfies GLP chain-of-custody requirements.​

Triplicate release testing: potency vs external std (HPLC 98.5-101.5%), dissolution >90% 15 min (USP App2, 50rpm), microbial limits USP <61/62>, related substances <0.5% any individual impurity. Retained composites support 36-month stability.​

Safety, Handling & Laboratory Precautions

Pellet manipulation requires Class 100 laminar flow or glovebox to contain respirable particles (<5 μm post-crush); PPE: static-free nitrile gloves, safety goggles, Tyvek® labwear per chemical hygiene plan. Avoid mechanical crushing—use validated dissolution apparatus.​

Process residues/wash solvents designated research chemical waste (RCRA U-listed analogs); alkaline neutralization + incineration 1100°C required; laboratory operations exclusively.​

Packaging, Labeling & Storage

Unit-dose Alu-Alu blister strips (10-100/pack) with desiccant sachet, child-resistant outer carton; 2D matrix barcode enables instantaneous batch certificate download. GHS-compliant labels: “Research Chemical C13H16FNO- HCl 50mg, UN3077 Class 9, Not for Human Use.”​

Store 15-30°C (<60% RH); 36-month expiry sealed; excursions to 2-8°C permitted 30 days.​

Intended Research Use & Market Positioning

50mg precision dosage optimizes low-level calibrators (0.5-50 ng/mL whole blood/plasma), LC-MS/MS IS preparation, and quantitative NMR standards eliminating gravimetric error propagation. Direct DBS card spiking achieves >98% recovery vs methanolic standards.

Strict laboratory research positioning—no clinical, veterinary, IND, or therapeutic designation. For research use only. Not for human or veterinary use. Not for clinical, diagnostic, or consumptive applications.

Ordering, Availability & Fulfillment

Qualified laboratory procurement via WooCommerce with institutional verification; volume discounts research consortia. Ambient shipping validated 7 days; 2-8°C optional.​

Support provides instrument method files (MRM transitions 222→179/204, IS d3-ketamine), matrix suppression data, and pellet dissolution kinetics.​

Legal & Regulatory Disclaimer

2F-Ketamine Pellets – 50mg constitute unregistered Schedule I research chemical absent FDA/EMA authorization for human investigational, veterinary, or commercial applications. Prohibited for administration, therapeutic investigation, or clinical research contexts; no ADME, toxicology, or human safety data beyond analytical characterization provided. For research use only. Not for human or veterinary use. Not for clinical, diagnostic, or consumptive applications.

Purchasers certify DEA research registration, institutional biosafety approval, and complete jurisdictional compliance governing possession, analysis, and disposition.​