Product Overview

S4 powder, commonly known as Andarine, is a brandless research-grade compound chemically designated as (S)-3-(4-(acetylamino)phenoxy)-2-hydroxy-2-methyl-N-(4-nitro-3-(trifluoromethyl)phenyl)propanamide, provided exclusively for analytical laboratory and investigative research purposes. It is supplied to qualified research institutions, pharmaceutical R&D laboratories, and analytical facilities needing a verified SARM analog for in vitro receptor binding studies, chromatographic method development, and structural characterization workflows. Each batch meets or exceeds ≥98% purity standards, supported by comprehensive analytical verification including certificates of analysis (COAs) for laboratory quality control integration.

As an unbranded generic reagent, S4 powder (Andarine) is positioned strictly for non-clinical research applications such as ligand affinity profiling and quantitative analytical method validation. No implications for biological testing, therapeutic applications, or administration protocols are intended or supported. For research use only. Not for human or veterinary use. Not for clinical, diagnostic, or consumptive applications.

Chemical Identity & Classification

S4 powder (Andarine) is classified as a nonsteroidal selective androgen receptor modulator (SARM) research chemical, serving as an analytical reference standard in pharmacology and receptor research contexts. Its specific chirality and substituted phenylpropanamide structure make it suitable for stereoselective binding studies in controlled laboratory environments.

Key identifiers include:

• Synonyms: S4; Andarine; GTx-007; S-4

• CAS number: 401900-40-1

• Molecular formula: C19H18F3N3O6

• Molecular weight: 441.36 g/mol

These specifications support precise cataloging in laboratory information management systems (LIMS), spectroscopic identification, and standardized documentation for research protocols.

Chemical & Physical Characteristics

S4 powder (Andarine) typically appears as a light yellow to yellow solid or crystalline powder, consistent with its formulation for analytical stability and handling. The powder form enables accurate gravimetric dispensing, dissolution into stock solutions, and aliquoting for calibration standards or high-throughput analytical formats.

Solubility characteristics include compatibility with DMSO, methanol (slightly soluble), and other polar aprotic solvents, facilitating preparation for liquid chromatography or cell-free assay applications. Density measures approximately 1.5 g/cm³, with melting point reported around 70-74°C or 151-155°C depending on polymorphic form; researchers should characterize batch-specific thermal behavior empirically. Physical stability under controlled humidity supports reliable long-term storage in research settings.

Purity & Analytical Verification

Guaranteed at ≥98% purity through industry-standard methods including high-performance liquid chromatography (HPLC), liquid chromatography-mass spectrometry (LC-MS), nuclear magnetic resonance (NMR) spectroscopy, and elemental analysis. These orthogonal techniques confirm chemical identity, quantify enantiomeric excess where applicable, profile synthetic impurities, and verify total nitrogen content against theoretical values.

Batch-specific COAs provide detailed chromatographic peak purity data, mass spectral confirmation of molecular ion, NMR spectral overlays matching reference standards, and residual solvent profiles compliant with analytical reagent specifications. These documents enable seamless method validation, instrument qualification, and data integrity compliance in professional laboratories. Availability supports integration with electronic laboratory notebooks and audit trails for reproducible quantitative workflows. Third-party re-analysis services offer additional verification layers for collaborative research programs.

Quality Control & Batch Integrity

Production utilizes batch-controlled manufacturing with unique lot numbering across all packaging and documentation, ensuring complete traceability from synthesis through distribution. Quality control protocols include raw material qualification, in-process monitoring of reaction completion and purification steps, final release testing for identity/potency/physical form, and stability-indicating assessments simulating storage and shipping conditions.​

Internal quality assurance maintains independence in release decisions, applying statistical sampling and process capability analysis to critical quality attributes like polymorphic consistency and particle size uniformity. Retained reference standards per lot facilitate cross-campaign bridging studies essential for multi-year investigations. This framework aligns with research-grade documentation standards suitable for institutional review boards, grant reporting, and technology transfer documentation, minimizing variability risks across procurement cycles.

Safety, Handling & Laboratory Precautions

S4 powder (Andarine) requires handling exclusively by trained laboratory personnel in certified fume hoods or glove boxes to prevent dust generation, inhalation, or contact exposure. Standard personal protective equipment includes nitrile gloves, safety goggles, laboratory coats, and respiratory protection as dictated by airborne particulate monitoring. Engineering controls such as local exhaust ventilation form the primary containment strategy.​

Users must consult the Material Safety Data Sheet (MSDS/SDS) for GHS hazard classifications, incompatible substances, and spill response procedures prior to manipulation. All storage, use, and disposal activities conform to institutional chemical hygiene plans and regulatory requirements for research chemicals; no occupational exposure limits, toxicological profiles, or medical guidance are provided.

Packaging, Labeling & Storage

Supplied in research-grade amber glass vials or HDPE containers with inert liners and tamper-evident seals to protect against moisture, light, and oxidative degradation. Labels include product name, CAS number, lot identifier, purity statement, hazard warnings, and storage instructions compliant with global chemical labeling standards.​

Recommended storage conditions maintain powder at refrigerated temperatures (2-8°C) in desiccated environments, minimizing hydrolytic or photolytic decomposition pathways. Containers remain sealed during non-use periods; batch-specific COA guidance supersedes general recommendations, with stability monitoring via HPLC recommended for extended projects.

Intended Research Use & Market Positioning

S4 powder (Andarine) supports applications in androgen receptor pharmacophore development, tissue-selective modulator screening, quantitative bioanalysis method validation, and structural analog library characterization within pharmaceutical discovery pipelines. It serves as a characterized standard for LC-MS/MS quantitation, chiral separation method optimization, and receptor binding displacement assays in non-clinical research frameworks.

Positioned strictly as a laboratory analytical reagent, it carries no designation for in vivo studies, human or veterinary applications, diagnostic reagents, or therapeutic development. For research use only. Not for human or veterinary use. Not for clinical, diagnostic, or consumptive applications.

Ordering, Availability & Fulfillment

Available for immediate secure purchase through compliant eCommerce platforms with real-time stock visibility and lot selection options. Checkout processes integrate payment processor standards, followed by professional packaging, tracked shipping, and digital COA/SDS delivery. Customer support addresses research-related documentation requests and order fulfillment inquiries.​

Fulfillment prioritizes current production lots to ensure optimal material freshness and performance consistency across orders. Bulk and custom aliquoting services support high-volume laboratory needs while maintaining chain-of-custody integrity.

Legal & Regulatory Disclaimer

S4 powder (Andarine) is supplied exclusively as a research chemical for legitimate laboratory investigations, without any regulatory approvals, registrations, or clearances for food, drug, supplement, or consumer applications. Buyers assume full responsibility for compliance with all applicable local, national, and international laws governing acquisition, possession, handling, and use of research compounds.

For research use only. Not for human or veterinary use. Not for clinical, diagnostic, or consumptive applications.