Buy Norflurazepam Powder

Product Overview

Norflurazepam Powder (CAS 2886-65-9) serves as a synthetic benzodiazepine reference material primarily utilized in forensic toxicology, chromatographic method development, and metabolic profiling studies within controlled laboratory environments. As a brandless, generic compound achieving ≥98% purity through controlled crystallization processes, it delivers researchers consistent quality for reproducible experimental outcomes investigating benzodiazepine analogs and metabolites. The fine powder format enables accurate gravimetric preparation of stock solutions and calibration standards, supporting applications from academic pharmacology departments to industrial quality control laboratories worldwide. Manufactured exclusively for non-clinical research purposes, this product aligns with international eCommerce compliance standards optimized for WooCommerce platforms serving qualified institutional buyers. Investigators value its defined particle characteristics for uniform dissolution kinetics in LC-MS workflows and stability-indicating HPLC assays. Exceptional long-term stability under desiccated conditions facilitates extended research timelines without purity degradation. For research use only. Not for human or veterinary use. Not for clinical, diagnostic, or consumptive applications.

Chemical Identity & Classification

Norflurazepam carries CAS number 2886-65-9, molecular formula C₁₅H₁₀ClFN₂O, and molecular weight 288.7 g/mol. Systematic IUPAC name: 7-chloro-5-(2-fluorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one. Common synonyms include N-desalkylflurazepam, norfludiazepam, and flurazepam metabolite. Classified as a 1,4-benzodiazepin-2-one derivative featuring 7-chloro and 5-(2-fluorophenyl) substitution, it functions as an analytical reference standard in mass spectrometry libraries, NMR structural elucidation, and retention time indexing. The desalkyl structure distinguishes it from N-substituted parent compounds, providing characteristic MS/MS transitions for targeted screening methods. These formal identifiers ensure precise cataloging in laboratory information management systems and facilitate method transfer across global research collaborations.

Chemical & Physical Characteristics

Norflurazepam Powder appears as a white to off-white crystalline solid with mean particle size D50 10-20 μm following micronization. It exhibits low aqueous solubility (<0.1 mg/mL at pH 7.4) but excellent compatibility with DMSO (>30 mg/mL), methanol (20 mg/mL), and acetonitrile for chromatographic mobile phase preparation. The compound demonstrates thermal stability with melting point 204-206°C under inert atmosphere, supporting thermal desorption techniques in GC-MS applications. Density measures 1.39 g/cm³, facilitating accurate volumetric dispensing in microgram weighing protocols. Solubility profile remains stable across pH 2-9 ranges, preventing precipitation during gradient elution. Hygroscopicity limited to <0.5% weight gain at 75% RH preserves anhydrous crystalline form essential for reproducible UV absorbance (ε268nm 28,000 M⁻¹cm⁻¹). Physical uniformity across batches enables consistent surface area exposure in dissolution rate determinations and solid-state stability assessments.

Purity & Analytical Verification

Every batch of Norflurazepam Powder meets or exceeds ≥98% purity, confirmed through orthogonal techniques including reversed-phase HPLC (C18 column, 254 nm detection), ¹H-NMR spectroscopy (DMSO-d6 solvent), LC-MS with ESI+ ionization, and GC-FID for residual solvent analysis. Certificates of Analysis detail chromatographic purity (>98.5% peak area), individual impurities (<0.10%), residual solvents (Class 2 <5000 ppm), and heavy metals (<20 ppm). These pharmacopeial-grade methods align with USP/EP reference standards, providing laboratories with documented chain-of-custody for accreditation purposes. Full spectral data including MS/MS fragmentation patterns and NMR assignments accompany digital COAs accessible post-purchase.

Quality Control & Batch Integrity

Production follows batch-controlled manufacturing with complete lot traceability from precursor qualification through final milling and packaging. Multi-stage in-process controls monitor reaction completion (>98% conversion), intermediate purification yields, and particle size distribution via laser diffraction. Final release testing includes assay potency, content uniformity, and microbial enumeration per USP <61> guidelines. Retained reference samples from each batch support stability investigations and retrospective retesting for up to seven years. Documentation standards incorporate batch manufacturing records, raw material certificates, and environmental monitoring logs mirroring ISO 17025 requirements. This systematic quality framework minimizes variability risks and ensures reliability for institutional research programs.

Safety, Handling & Laboratory Precautions

Handle Norflurazepam Powder exclusively in certified chemical fume hoods (>100 fpm face velocity) equipped with appropriate personal protective equipment including nitrile gloves (15 mil thickness), safety goggles (ANSI Z87.1), laboratory coats, and respiratory protection for powder operations. Conduct weighing and transfers using enclosed analytical balances with secondary containment trays. Store separately from oxidizing agents, strong acids, and alkalies in dedicated chemical storage cabinets. Spill response employs non-reactive absorbents followed by HEPA vacuuming and decontamination per chemical hygiene plan protocols. Material Safety Data Sheets provide comprehensive GHS hazard classifications, incompatibilities, and waste disposal guidance supporting safe laboratory practices.

Packaging, Labeling & Storage

Norflurazepam Powder ships in amber glass vials with PTFE-lined screw caps and integrated desiccants, providing inert moisture barrier protection. Units feature tamper-evident seals and overwrap packaging for transit security. Labels comply with GHS standards displaying CAS 2886-65-9, purity specification, hazard pictograms, handling precautions, and research-only designation. Recommended storage utilizes desiccated conditions at -20°C in darkness, maintaining stability for minimum five years; room temperature storage (15-25°C) acceptable for shorter access periods. Reseal containers immediately after use to prevent humidity exposure and ensure long-term analytical performance.

Intended Research Use & Market Positioning

Norflurazepam Powder targets analytical method validation, forensic toxicology screening, reference standard preparation, and benzodiazepine metabolism studies across academic institutions, contract research organizations, and government laboratories. The powder format supports quantitative recovery experiments, calibration curve generation, and limit of quantitation determinations in complex biological matrices. Positioned as a high-purity generic alternative to proprietary standards, it addresses procurement needs for laboratories conducting proficiency testing, regulatory submissions, and quality assurance programs. Bulk quantities available for high-volume method development initiatives.

Ordering, Availability & Fulfillment

Norflurazepam Powder maintains ready stock for immediate processing through secure WooCommerce checkout supporting international payment methods. Orders received process within 24 business hours with tracked discreet shipping worldwide. Comprehensive customer support handles COA requests, bulk pricing inquiries, and delivery status updates. Compliant packaging and documentation facilitate seamless customs clearance for institutional research deliveries.

Legal & Regulatory Disclaimer

Norflurazepam Powder (CAS 2886-65-9) sold strictly for laboratory research purposes only. Not for human or veterinary use. Not for clinical, diagnostic, or consumptive applications. Buyers assume full responsibility for compliance with applicable local, national, and international laws and regulations. No warranties extend to unauthorized applications; verify legal status prior to purchase.