Product Overview

MDPHP Powder (freebase), known chemically as 3,4-Methylenedioxy-α-pyrrolidinohexanophenone, stands as a brandless, high-purity (≥98%) research chemical tailored for laboratory investigations in synthetic organic chemistry and chromatographic reference standards. This methylenedioxy-substituted pyrrolidinophenone supports precise analytical protocols within controlled research environments, enabling method development and validation across diverse scientific applications. For research use only. Not for human or veterinary use. Not for clinical, diagnostic, or consumptive applications.

Researchers value its consistent quality for structural elucidation studies and impurity profiling in pharmaceutical R&D. The freebase form offers enhanced solubility characteristics compared to salt variants, facilitating reproducible experimental outcomes. Available immediately for purchase by qualified laboratories maintaining strict compliance protocols. Stock reliability ensures uninterrupted workflow integration for ongoing projects.

Global research institutions rely on such reagents to benchmark synthetic cathinone analogs without introducing variables from branded formulations. Procurement streamlines through secure platforms designed for institutional buyers seeking high-integrity materials.​

Chemical Identity & Classification

MDPHP Powder (freebase) features molecular formula C17H23NO3 and molecular weight 289.4 g/mol, distinguishing it from the hydrochloride salt (C17H24ClNO3, 325.8 g/mol). Key synonyms include Methylenedioxypyrrolidinohexiophenone, 3′,4′-Methylenedioxy-α-pyrrolidinohexanophenone, and MDPHP freebase. It classifies as a synthetic cathinone derivative and analytical reference material within the pyrrolidinophenone subclass.

These identifiers enable precise matching in spectral libraries and regulatory documentation for forensic toxicology and metabolic pathway research. The extended hexyl chain differentiates it from shorter analogs like MDPV (C16H21NO3), influencing lipophilicity profiles critical for separation science. Formal classification supports its role in comparative structure-activity studies without therapeutic connotations.

Chemical & Physical Characteristics

MDPHP Powder (freebase) appears as a white to off-white fine powder, exhibiting good solubility in organic solvents such as DMSO, acetonitrile, and dichloromethane, while showing limited aqueous solubility. Stability persists under inert atmospheres at ambient temperatures, with calculated logP values between 3.5-4.2 reflecting substantial hydrophobic character suited to reversed-phase chromatography. Topological polar surface area measures approximately 38.8 Ų, aiding predictions for LC-MS behavior.

The freebase configuration enhances volatility compared to protonated salts, beneficial for GC-MS applications. Crystal lattice absence in powder form promotes uniform dispersion during sample preparation. Physical traits align with methylenedioxy-substituted phenones, including conformational flexibility from the hexyl chain’s rotational dynamics on picosecond timescales.

Melting point approximations fall within 100-120°C range under controlled conditions, while boiling points exceed 330°C, supporting thermal stability in vapor-phase analyses. These neutral descriptors inform handling without implying performance metrics.​

Purity & Analytical Verification

Every MDPHP Powder (freebase) batch exceeds 98% purity, rigorously confirmed through orthogonal methods including high-performance liquid chromatography (HPLC) at 254 nm, gas chromatography (GC-FID), proton nuclear magnetic resonance (NMR) spectroscopy, and liquid chromatography-mass spectrometry (LC-MS). COA documents reveal impurities below 0.5%, with monoisotopic mass locked at 289.1678 Da and characteristic fragments like the methylenedioxybenzoyl ion at m/z 149.

HPLC chromatograms display baseline resolution of enantiomers when chiral columns apply, essential for stereospecific research. NMR confirms pyrrolidine ring integrity and dioxole substitution patterns. LC-MS fragmentation patterns serve as diagnostic fingerprints, reproducible across lots for quantitative calibration curves spanning 0.1-100 µg/mL. Third-party labs corroborate findings via ISO-accredited methods upon request.

Trace metal analysis via ICP-MS and residual solvent screening per ICH Q3C guidelines further validate suitability for sensitive assays. This multi-tiered verification builds confidence in data integrity for publication-grade experiments.​

Quality Control & Batch Integrity

Production adheres to batch-controlled synthesis tracing raw materials through bromination-amination or Mannich pathways, with in-process controls monitoring yield and intermediates. Each lot receives unique identifiers linked to retention samples stored for five years, comprehensive synthesis logs, and raw spectral data. Internal QC employs statistical process control to cap variability at <1% relative standard deviation across purity metrics.

Optional third-party auditing by accredited facilities reinforces claims, including enantiomeric excess determination via chiral HPLC. Documentation packages integrate with electronic lab notebooks and LIMS, streamlining compliance audits. Long-term stability monitoring under ICH Q1A conditions confirms shelf-life exceeding 24 months at -20°C. This framework minimizes risks in multi-site collaborative research.

Safety, Handling & Laboratory Precautions

Handle MDPHP Powder (freebase) exclusively in certified chemical fume hoods by personnel versed in synthetic organic hazards, donning nitrile or butyl gloves, chemical-resistant aprons, safety goggles, and face shields. Conduct operations over secondary trays with absorbent spill media in areas equipped with emergency eyewash stations. Consult provided Safety Data Sheet (SDS/MSDS) for exposure limits and incompatibility data.

Avoid ignition sources given flash point considerations; neutralize spills with 5% sodium bicarbonate prior to disposal. Waste streams follow RCRA or equivalent hazardous classifications via licensed handlers. Training records and SOPs mandatory for lab authorization.​

Packaging, Labeling & Storage

Dispensed in 5-20 mL amber borosilicate glass vials sealed with PTFE-faced silicone septa and crimped aluminum caps for tamper evidence and puncture access. Labels comply with GHS, displaying CAS proxy, batch code, net weight, ≥98% purity declaration, and pictograms for irritant and health hazards. Store sealed at -20°C or below in desiccated freezers, away from alkalies and strong oxidants, preserving integrity for 36+ months.

Nitrogen-purged headspaces prevent autoxidation; secondary vacuum-sealed foil pouches enhance transit protection. Labeling supports barcode scanning for inventory automation.​

Intended Research Use & Market Positioning

MDPHP Powder (freebase) finds application in analytical method validation for LC-MS/GC-MS detection limits below 1 ng/mL, forensic toxicology screening panels, metabolic transformation studies via hepatocyte models, and synthetic route optimization in pharmaceutical impurity profiling. Academic programs incorporate it into graduate-level spectroscopy and chromatography curricula. Positioned as a premium, economical freebase standard outperforming hydrochloride in solubility-limited assays.

Serves industrial R&D in materials science for polymer additive interactions and environmental fate modeling. Exclusively for non-biological laboratory contexts, it meets global demands for traceable pyrrolidinophenone references amid rising regulatory scrutiny.

Ordering, Availability & Fulfillment

Fully stocked for same-day dispatch via WooCommerce-secured checkout processing Visa/Mastercard, ACH transfers, and privacy-focused cryptocurrencies. Discreet, temperature-controlled shipping through DHL Express or FedEx Priority reaches 95% of destinations in 3-7 business days, complete with customs declarations as “research reagent.” Dedicated support resolves COA requests, backorder alerts, and bulk negotiations within 24 hours.

Volume-based tiering offers 10-30% discounts for 10g+ orders; subscription models ensure priority allocation for recurrent institutional needs. Real-time inventory portal accessible post-registration.​

Legal & Regulatory Disclaimer

This product sells strictly for laboratory research purposes only, not for human or veterinary use, clinical, diagnostic, or therapeutic applications of any kind. Buyers bear complete responsibility for ascertaining and maintaining compliance with all pertinent local, national, and international regulations governing research chemicals, including import/export controls and controlled substances schedules. Pre-order verification of jurisdictional legality mandatory; seller disclaims all liability for regulatory infractions or unintended applications. For research use only. Not for human or veterinary use. Not for clinical, diagnostic, or consumptive applications.