Buy HXE Powder

Product Overview

HXE Powder offers a brandless, high-purity (≥98%) arylcyclohexylamine compound, systematically 2-(ethylamino)-2-(3-hydroxyphenyl)cyclohexan-1-one, formulated exclusively for professional laboratory research and analytical standards. Bearing CAS 1620054-73-0, this material—also termed 3′-hydroxy-2-oxo-PCE or O-desmethylmethoxetamine—functions as a key reference in forensic toxicology, metabolite identification, and structural elucidation studies within qualified research facilities. The fine powder morphology ensures optimal homogeneity, precise gravimetric handling, and stability for calibration standards and library development in advanced instrumental workflows. For research use only. Not for human or veterinary use. Not for clinical, diagnostic, or consumptive applications.

Research institutions leverage HXE Powder’s documented spectral signatures for LC-QTOF-MS confirmation, impurity profiling of hydroxylated arylcyclohexylamines, and method validation against methoxetamine metabolites. Rigorous batch controls guarantee consistency, positioning it as an essential tool for non-clinical investigations in analytical chemistry and reference material programs.

Chemical Identity & Classification

HXE features CAS 1620054-73-0, molecular formula C14H19NO2, and molecular weight 233.31 g/mol. IUPAC designation 2-(ethylamino)-2-(3-hydroxyphenyl)cyclohexanone aligns with synonyms Hydroxetamine, HXE, and 3-hydroxy-2-oxo-PCE. InChI=1S/C14H19NO2/c1-2-15-14(9-4-3-8-13(14)17)11-6-5-7-12(16)10-11/h5-7,10,15-16H,2-4,8-9H2,1H3 and InChIKey VEXZGXHMUGYJMC-UHFFFAOYSA-N enable database matching, while PubChem CID 163192347 supports computational modeling. This compound classifies as an analytical reagent and arylcyclohexylamine reference standard.

The meta-hydroxy substitution on the phenylcyclohexanone scaffold differentiates it structurally, yielding unique MS/MS transitions for isomer resolution in forensic panels.​

Chemical & Physical Characteristics

HXE Powder presents as a white to off-white crystalline solid with uniform particle distribution ideal for microscale analyses. Solubility reaches 12 mg/mL in DMSO, 8 mg/mL in ethanol/DMF, and ~1.2 mg/mL in PBS (pH 7.2), reflecting logP ~2.8 and TPSA 46.5 Ų. Density ~1.15 g/cm³ and low vapor pressure confirm non-volatility for safe laboratory manipulation.

UV λmax ~280 nm (phenolic influence) aids HPLC detection; exact mass [M+H]+ 234.1489 Da enables HRMS verification. Thermal profile supports ambient-to-refrigerated storage without degradation.

Purity & Analytical Verification

Batches guarantee ≥98% purity via HPLC (>98.2% area, 220 nm), GC-EI-MS, 1H-NMR (DMSO-d6: ethyl triplet 1.05 ppm, phenolic OH ~9.5 ppm broad), 13C-NMR, and LC-HRMS (m/z 234.1489 ±4 ppm). Process impurities <0.4%, solvents <3000 ppm ICH Q3C, metals <15 ppm ICP-MS.

COAs furnish chromatograms, spectra vs. certified standards, KF moisture (<0.5%), confirming quantitative suitability per forensic guidelines.​

Quality Control & Batch Integrity

Regioselective synthesis from 3-hydroxyphenyl precursors and cyclohexanone employs reductive amination/crystallization, with interim HPLC/TLC controls. Lot traceability from >99% inputs through sieved powder (D90 <30 μm). Third-party FTIR (O-H 3400 cm⁻¹, C=O 1712 cm⁻¹) and EA (C 72.1%, H 8.2%, N 6.0%) validate composition.​

ICH stability (25°C/60%RH) retains >97% at 24 months; retention protocols support retesting.​

Safety, Handling & Laboratory Precautions

Handle in ventilated enclosures with PPE: nitrile gloves, goggles, lab coats. Minimize dust via enclosed systems; segregate from oxidizers/acids. SDS notes irritancy (H315/H319/H335); spills use inert absorbents, NaHCO3 quench, hazwaste disposal.

Packaging, Labeling & Storage

Amber vials (PTFE septa, tamper seals) in desiccated pouches. GHS labels detail CAS, purity, hazards, COA QR. Store -20°C dark; 36-month stability.

Intended Research Use & Market Positioning

Supports NPS toxicology (LODs 2-20 ng/mL), metabolite mapping, R&D of hydroxylated dissociatives. Fills reference gaps for methoxetamine pathways in ISO-accredited labs.

Ordering, Availability & Fulfillment

WooCommerce stock with secure checkout; tracked global dispatch as research reagents. Bulk/COA support available.​

Legal & Regulatory Disclaimer

HXE Powder sold strictly for research purposes only, not for human or veterinary use, clinical, diagnostic, or therapeutic applications. Buyers ensure regulatory compliance. For research use only. Not for human or veterinary use. Not for clinical, diagnostic, or consumptive applications.