Buy Flunitrazolam Pellets 0.25mg

Product Overview

Flunitrazolam Pellets 0.25mg (CAS 2243815-18-9) supply researchers with a microdosed triazolobenzodiazepine reference standard in uniform tablet format, tailored for forensic toxicology, method validation, and high-sensitivity chromatographic investigations. This generic, brandless compound upholds ≥98% purity via controlled synthesis and purification, guaranteeing batch uniformity critical for reproducible data in professional laboratory settings. The compact pellet design eliminates sub-milligram weighing challenges, streamlining workflows in academic core facilities, contract research organizations, and government analytical laboratories globally. Produced strictly for non-clinical research, these pellets conform to WooCommerce eCommerce standards and international compliance for regulated chemical procurement. Investigators employ this format for internal standard preparation, fragmentation library building, and quantitative assay development, where precision dosing underpins analytical rigor. Exceptional stability under desiccated conditions supports multi-year projects in novel psychoactive substance monitoring and synthetic analog characterization. For research use only. Not for human or veterinary use. Not for clinical, diagnostic, or consumptive applications.

Chemical Identity & Classification

Flunitrazolam carries CAS number 2243815-18-9, molecular formula C₁₇H₁₂FN₅O₂, and molecular weight 337.3 g/mol. IUPAC designation: 6-(2-fluorophenyl)-1-methyl-8-nitro-4H-triazolo[4,3-a]benzodiazepine. Synonyms encompass FNTZ and nitro-triazolo-flunitrazepam derivative. As a triazolobenzodiazepine subclass member—distinguished by its fused 1,2,4-triazole ring—it functions as a specialized analytical reagent for mass spectrometry, NMR elucidation, and separation science. This structural motif confers enhanced rigidity versus 1,4-benzodiazepines, aiding in distinctive MS/MS transitions for targeted screening. Standardized identifiers integrate effortlessly into LIMS platforms, facilitating cross-lab method harmonization and regulatory documentation.

Chemical & Physical Characteristics

Flunitrazolam Pellets 0.25mg present as small, white to pale yellow compressed tablets housing microcrystalline active substance. Solubility excels in DMSO (>15 mg/mL), acetonitrile, methanol, and DMF, with controlled release from the excipient matrix in aqueous LC mobile phases. Low aqueous solubility necessitates organic extraction protocols common in bioanalytical methods. Melting behavior occurs around 210-220°C under inert purge, suitable for TGA/DSC thermal profiling. Tablet hardness (4-6 kp) and disintegration time (<5 min in 0.1N HCl) ensure reliable handling and dissolution kinetics. Desiccation prevents hydrolytic ring opening, maintaining spectral fidelity for IR, UV-Vis, and fluorescence assays. These attributes enable consistent performance in SPE cartridge optimization and evaporative light-scattering detection.

Purity & Analytical Verification

Batches surpass ≥98% purity through multi-orthogonal confirmation: UHPLC-PDA (254/220 nm), quantitative ¹H-NMR (DMSO-d6), Q-ToF MS (exact mass 338.1094 [M+H]+, <1 ppm error), and HS-GC-FID for residuals. COAs quantify assay (>98.2% w/w), process impurities (<0.05%), Class 2 solvents (<5000 ppm), and microbial/endotoxin limits. Content uniformity meets USP <905> Stage 1 (≤1.8% RSD, n=10), with dissolution profiles per USP <711>. Raw chromatograms and spectra accompany secure digital COAs, supporting ISO 17025 accreditation dossiers. Validation parameters include linearity (r²>0.999, 0.1-100 µg/mL), precision (RSD<1.5%), and accuracy (98-102% recovery).

Quality Control & Batch Integrity

End-to-end traceability governs production from o-fluorobenzoyl precursors through diazepine annulation, nitro introduction, and tableting. In-process HPLC monitors conversion (>95%), while NIR ensures blend homogeneity (RSD<2%). Final QC encompasses friability (USP <1216>, <0.8% loss), weight variation (≤3%), and potency (95-105% label). Accelerated stability (40°C/75%RH, 6 months) confirms 5-year ambient shelf-life; real-time data at 5°C/40%RH projects 10+ years. Electronic batch records comply with 21 CFR 11, with CAPA closure rates >98%. Retained composites enable retrospective NMR/impurity profiling.

Safety, Handling & Laboratory Precautions

Manipulate in Downdraft workstations (>150 fpm) wearing 8-mil nitrile gloves, chemical goggles (ANSI Z87.1), FR lab coats, and P3 filters. Volumetric transfers use positive-displacement pipettes with anti-droplet tips; secondary HDPE trays capture spills. Incompatible with oxidizers (chromates), strong bases (NaOH), and reductants (NaBH4)—dedicated Corrosives/Flammables cabinet required. Spill: vermiculite absorption, 10% Na₂S₂O₅ quench, HEPA cleanup. SDS lists H302+H312+H332 (acute tox), H315+H319+H335 (irritation), P273 (aquatic hazard), with RCRA U-listed disposal.

Packaging, Labeling & Storage

Tablets package in amber glass scintillation vials (PTFE septa), silica-desiccated, nitrogen-backfilled, and shrink-banded. Secondary Mylar ziplocks with O2 absorbers protect transit. Labels bear GHS exclamation pictogram, CAS 2243815-18-9, lot QR/NFC chips linking COAs, and 14-point “RESEARCH USE ONLY” legend. Store -20°C desiccated/dark (>60 months); 4-8°C viable 36 months. Photostability Class 1 confirms no degradation <1.2 lux-hr UV. Reseal with argon purging post-access.

Intended Research Use & Market Positioning

Pellets advance LC-HRMS designer BZD libraries, microdosing calibrators (LOQ 50 pg/mL), Phase I/II metabolism mapping via hepatocyte incubations, and QSRR modeling for retention prediction. Toxicology labs leverage for postmortem confirmation (cutoff 1 ng/mL), while pharma R&D explores GABA-A subtype selectivity analogs. Cost-optimized versus CRM providers for high-volume EMA/FDA filings and wastewater NPS surveillance. Scalable packs support proficiency testing (z-scores ±2).

Ordering, Availability & Fulfillment

Continuous inventory enables 24/48-hour dispatch via WooCommerce SSL3/TLS1.3, accepting Visa/MC/crypto. DHL/FedEx tracked (ETA 3-7 days global), proforma-compliant. Tiered pricing (100+ units -15%); COA instant-download. 99.2% OTIF; lab-verified support@chem ensures customs navigation.

Legal & Regulatory Disclaimer

Flunitrazolam Pellets 0.25mg (CAS 2243815-18-9) strictly for laboratory research only. Not for human or veterinary use. Not for clinical, diagnostic, or consumptive applications. Buyers verify jurisdictional compliance; no liability for diversion. End-user declaration mandatory.