Product Overview

a-PiHP Crystal Chunks (α-Pyrrolidinoisohexanophenone) provide a brandless, high-purity (≥98%) research chemical for laboratory studies in synthetic cathinone reference standards and chromatographic method development. These chunky crystals support precise structural analysis and impurity profiling in controlled forensic and pharmaceutical research settings. For research use only. Not for human or veterinary use. Not for clinical, diagnostic, or consumptive applications.

Laboratories favor the chunk format for reduced surface area exposure versus powders, maintaining stability during long-term storage and handling. The isohexyl chain distinguishes it from straight-chain analogs like α-PHP, enabling differential retention studies. Stocked for immediate compliant purchase by qualified institutions worldwide.

This reagent fills critical gaps in NPS analytical panels, supporting global surveillance through standardized reference materials. Secure WooCommerce platforms ensure institutional-grade traceability.​

Chemical Identity & Classification

a-PiHP Crystal Chunks feature molecular formula C16H23NO and molecular weight 245.36 g/mol, with IUPAC name 4-methyl-1-phenyl-2-(pyrrolidin-1-yl)pentan-1-one. Synonyms include α-PiHP and α-Pyrrolidinoisohexanophenone. Classified as a pyrovalerone analog within synthetic cathinone reference materials, possessing a chiral α-carbon.

SMILES CC(C)CC(N1CCCC1)C(=O)c2ccccc2 and InChIKey notation facilitate spectral database integration. LogP 3.4 and TPSA 29.5 Ų predict optimal reversed-phase behavior. Positional isomerism at the isohexyl differentiates MS fragments from α-PHP.​

Chemical & Physical Characteristics

White crystalline chunks dissolve readily in DMSO (>20 mg/mL), methanol, and dichloromethane, with low aqueous solubility. UV maxima at 255 nm guides detection; melting point 108-115°C for HCl salt supports GC thermal profiles. Chunk morphology (2-8 mm) ensures uniform sampling (RSD <1%).

Stability under inert conditions prevents keto-enol tautomerism; vapor pressure suits headspace analysis. Physical properties align with pyrrolidinophenone expectations, optimizing LLE recoveries >95%.​

Purity & Analytical Verification

Batches ≥98% pure via HPLC (C18 gradient), GC-MS (EI m/z 98/245), NMR (CDCl3, pyrrolidine 1.8-3.2 ppm), LC-HRMS [M+H]+ 246.1852. COA limits impurities <0.5%, solvents ICH-compliant. Chiral HPLC resolves enantiomers Rs>2.

Orthogonal methods confirm diagnostic ions m/z 175 (benzoyl), 70 (pyrrolidinium). Third-party validation available.​

Quality Control & Batch Integrity

Batch synthesis traces via alpha-amination of isohexanophenone, with IPC HPLC and retention samples. SPC maintains purity variation <0.5%. Digital records ensure LIMS compatibility.

Safety, Handling & Laboratory Precautions

Handle in fume hoods with nitrile gloves, goggles, lab coats. Use spill containment; consult SDS for GHS details. Dispose as hazardous waste.​

Packaging, Labeling & Storage

Amber vials with PTFE septa, tamper-evident seals, GHS labels. Store -20°C desiccated for 36+ months.​

Intended Research Use & Market Positioning

Supports LC-MS LOQ <0.5 ng/mL, forensic validation, impurity profiling. Positioned for NPS research labs globally.

Ordering, Availability & Fulfillment

In stock for tracked shipping via WooCommerce. Bulk discounts available.

Legal & Regulatory Disclaimer

Sold for research purposes only, not for human or veterinary use, clinical, diagnostic, or therapeutic applications. Buyers ensure regulatory compliance. For research use only. Not for human or veterinary use. Not for clinical, diagnostic, or consumptive applications.