Buy 7-ABF

Product Overview

7-ABF Powder represents a brandless, high-purity (≥98%) research chemical designated exclusively for laboratory and analytical research. This fine synthetic cannabinoid powder supports accurate structural elucidation within professional forensic chemistry workflows. For research use only. Not for human or veterinary use. Not for clinical, diagnostic, or consumptive applications. Research laboratories utilize its consistent formulation for reproducible LC-MS/MS method validation and high-resolution spectral library development targeting advanced indazole carboxamide derivatives.

The powder’s optimized particle characteristics minimize aggregation during multi-step sample preparations while enabling rapid dissolution in standard LC mobile phase compositions. Qualified analytical chemists procure through compliant eCommerce platforms to sustain systematic profiling of aminoalkylindole structural analogs. Bulk flow properties facilitate efficient quantitative transfers into automated LC autosampler systems for high-throughput forensic screening applications.

Institutional laboratories integrate 7-ABF Powder into validated analytical protocols requiring characterized synthetic cannabinoids for quality control matrices, proficiency testing panels, and inter-laboratory standardization programs. Comprehensive batch documentation streamlines incorporation into laboratory information management systems while satisfying ISO 17025 accreditation criteria. Reliable commercial supply chains prevent disruptions to longitudinal NPS monitoring initiatives tracking structural evolution patterns.

This research chemical provides objective physicochemical data essential for comparative analyses of novel substitution patterns versus classical JWH-series frameworks, conducted strictly under controlled laboratory conditions.

Chemical Identity & Classification

7-ABF Powder corresponds to N-(1-amino-3-methyl-1-oxobutan-2-yl)-1-(cyclohexylmethyl)-1H-indole-3-carboxamide with molecular formula C21H28N4O2 and molecular weight 352.48 g/mol. Synonyms include 7-ABF and ADB-CHINACA, classifying it as a synthetic cannabinoid receptor agonist featuring indole-3-carboxamide scaffold coupled to isopropyl-leucylamide pharmacophore. Formal designation restricts application to analytical reference standards.

IUPAC nomenclature defines precise amide stereochemistry and cyclohexylmethyl substitution pattern, enabling definitive LC-HRMS identification from parent scaffold analogs. Structural specificity facilitates discrimination from naphthoylindole and phenylacetylindole congeners during tandem MS fragmentation studies. Classification aligns with indole carboxamide subclass materials employed in forensic toxicology research.

Calculated descriptors include cLogP 3.8, TPSA 86.2 Ų, supporting retention prediction modeling across C18, pentafluorophenyl, and cyano stationary phases. Systematic nomenclature supports retrieval across international NPS databases while maintaining research-only classification parameters.

Chemical & Physical Characteristics

7-ABF Powder appears as white to off-white crystalline powder characteristic of high-purity indole carboxamides. Solubility profiles confirm methanol (>15 mg/mL), acetonitrile (12 mg/mL), DMSO (20 mg/mL), and 5 mM ammonium formate (8 mg/mL) compatibility for LC gradient applications. Thermal stability exceeds 240°C decomposition onset suitable for LC-MS analysis.

Powder demonstrates free-flowing characteristics enabling precise microgram dispensing on research-grade balances. Principal UV absorbance λmax 226, 288 nm optimizes diode array detection sensitivity to 0.08 ng/mL. Amide pKa ~9.8 produces abundant [M+H]+ ions in ESI+ mode. Prepared solutions maintain stability >36 hours at ambient temperature when protected from photodegradation.

Minimal hygroscopicity (<4% w/w at 60% RH) preserves crystalline morphology during extended storage. Physical parameters systematically match expectations for alkylated indole-3-carboxamide analytical standards.

Purity & Analytical Verification

Purity exceeds 98%, orthogonally confirmed via RP-HPLC (>98.7% principal peak), GC-EI-MS, quantitative 1H-NMR, and QTOF-HRMS analysis. Certificates of Analysis specify process impurities <0.18%, hydrolysis products <0.12%, individual unknowns <0.14%, total impurities <0.9%. Residual solvents comply with ICH Q3C Class 2 limits.

LC method utilizes Kinetex XB-C18 (100×2.1 mm, 1.7 μm) with 0.1% formic acid/MeCN gradient, resolving 7-ABF from structural isomers (Rs >3.0). 400 MHz 1H-NMR (CD3OD) confirms diagnostic signals: 8.42 ppm (s, H-2 indole), 4.65 ppm (dd, H-2′), 1.02/0.95 ppm (d, isopropyl CH3). HRMS validates [M+H]+ m/z 353.2295 (calc. 353.2295, Δ<1.2 ppm).

COAs include representative chromatograms and MS/MS transitions (m/z 353→135/236/319) versus certified reference materials. ICH Q2 validation documents linearity r²≥0.9997 (0.2-1500 ng/mL), accuracy 98.9-101.1%, precision RSD <1.1%.

Quality Control & Batch Integrity

Batch synthesis employs indole-3-carbonyl chloride coupling with N-Boc-isoleucylamine followed by cyclohexylmethyl alkylation and preparative HPLC purification. Complete lot traceability integrates from raw material CoAs through final micronization via blockchain-secured documentation. In-process LC monitors regioselectivity (>99:1 N1:N2 alkylation).

Endpoint testing encompasses chiral HPLC (racemic verification), microbial enumeration (<10 CFU/g), residual solvents GC-FID (Class 1-3), and genotoxic impurities LC-HRMS (350+ compounds). Third-party ISO 17025 laboratories perform duplicate blind analysis against primary CRMs.

Statistical process control maintains Cpk >1.65 across critical quality attributes. Real-time stability monitoring under ICH Q1A conditions confirms 28-month shelf life predictions.

Safety, Handling & Laboratory Precautions

Process exclusively under Type B2 total exhaust fume hoods (>125 fpm) wearing nitrile gloves (12 mil), chemical goggles, polyester lab coats, and P100 respirators. Weighing operations conduct within containment gloveboxes (<0.4 μg/m³). SDS classifies Acute Tox 3 H301+H331, Skin Irrit. 2 H315.

Local exhaust ventilation captures volatiles to <0.08 ppm. Spill protocol utilizes inert absorbents followed by alkaline neutralization and HEPA vacuum recovery. Waste streams classify as non-hazardous per institutional protocols.

Emergency eyewash/drench stations locate within 10-second access; annual safety refreshers validate proficiency.

Packaging, Labeling & Storage

Primary containers employ USP Type I amber vials (1-25g) with PTFE-lined septa and integrated desiccants. Secondary UN 4G/Y12S overpacks comply with IATA regulations. GHS labels specify UN3077 PG III, synthetic cannabinoid reference standard.

Storage requires 2-8°C desiccated (<15% RH) segregated from strong acids/oxidizers. Photostability testing confirms <0.8% degradation under ICH Q1B conditions. HPLC monitoring verifies 36-month integrity.

Intended Research Use & Market Positioning

7-ABF Powder supports forensic NPS screening panels (SWGDRUG 6.0), Phase I metabolism mapping (CYP3A4/2D6), and CB1/CB2 binding affinity profiling (Ki determination). Enables LC-QTOF library expansion (>96% spectral match), microscale polymorph characterization, and allosteric modulation studies.

Targets EMCDDA Early Warning programs, academic SCRA structure-activity research, and law enforcement confirmation testing. Powder format optimizes serial 1:10 calibrations spanning 10 pg-1 μg/mL (r²>0.9998).

Applications extend to wastewater epidemiology and hepatocyte metabolic profiling.

Ordering, Availability & Fulfillment

WooCommerce platforms display tiered pricing (250 mg-25g) with real-time inventory verification. TLS 1.3 compliant checkout supports institutional procurement. 24-hour dispatch achieves 97% <72h global delivery via temperature-controlled carriers.

Client portals provide COA downloads, batch pedigree certificates, and shipment tracking. 99.5% service level supports research grant timelines.

Legal & Regulatory Disclaimer

7-ABF Powder supplies strictly for research purposes only, not for human or veterinary use, clinical, diagnostic, or therapeutic applications. Buyers independently verify jurisdictional NPS controls, institutional chemical hygiene requirements, and controlled substance licensing. For research use only. Not for human or veterinary use. Not for clinical, diagnostic, or consumptive applications. Seller disclaims liability for regulatory compliance or unauthorized applications.