Buy 6-APB Pellets 130mg

Product Overview

6-APB Pellets 130mg deliver a brandless, high-purity (≥98%) benzofuran derivative, chemically 6-(2-aminopropyl)benzofuran, optimized for laboratory research in synthetic chemistry, forensic validation, and spectroscopic characterization. The precise 130mg pressed format eliminates weighing variability, supporting consistent sample preparation for LC-MS method development, NMR structural confirmation, and receptor binding assays in controlled settings. Researchers across academic institutions, industrial R&D facilities, and analytical laboratories select this form for its uniformity and ease of integration into high-throughput workflows. Batch production ensures low lot-to-lot variation, critical for longitudinal studies on molecular analogs and impurity profiling. The compound’s benzofuran scaffold enables investigations into heterocyclic reactivity and chromatographic behavior under diverse conditions. Stable matrix composition maintains integrity during storage and transport, facilitating reliable experimental replication. For research use only. Not for human or veterinary use. Not for clinical, diagnostic, or consumptive applications.

Chemical Identity & Classification

6-APB corresponds to CAS 286834-84-2 (hydrochloride salt), with freebase at 286834-85-3. Molecular formula C11H13NO (freebase; C11H14NO- HCl for salt), molecular weight 175.23 g/mol (freebase), 211.69 g/mol (HCl). IUPAC name: 1-(1-benzofuran-6-yl)propan-2-amine; synonyms: benzo fury, α-methyl-6-benzofuranethanamine. SMILES: CC(N)CC1=CC2=C(C=C1)C=CO2. InChI: InChI=1S/C11H13NO/c1-8(12)4-9-2-3-10-7-11(13-6-5-10)9/h2-3,5-8H,4,12H2,1H3. Classified as a synthetic benzofuran, phenethylamine analog, and forensic reference material for NPS (novel psychoactive substance) identification in toxicology and drug metabolism research.

Chemical & Physical Characteristics

6-APB Pellets appear as uniform, white to off-white compressed tablets (diameter ~6-8 mm), with binder-excipient matrix ensuring >95% active content uniformity. Freebase solubility: >20 mg/mL DMSO, ethanol, DMF; ~1 mg/mL water (pH 7.2); hydrochloride enhances aqueous solubility to 50 mg/mL. Melting point 185-190°C (HCl salt, DSC); decomposition >250°C. pKa ~9.8 (amine), logP 2.1-2.4. UV λmax: 207, 246, 276, 285 nm. IR principal bands: 3300 cm⁻¹ (N-H), 750 cm⁻¹ (benzofuran). Hygroscopic; friability <1% per USP <1216>. Dissolution profile: >85% in 30 min (pH 6.8 phosphate buffer), suitable for simulated GI tract studies in vitro. Vapor pressure negligible (<10⁻⁶ mmHg, 25°C); flash point ~120°C. Racemic unless specified; chiral HPLC resolves enantiomers (Rs >1.5). These parameters support GC-MS (EI m/z 175 [M]+), LC-MS (ESI [M+H]+ 176.1), and dissolution kinetics research.

Purity & Analytical Verification

Each pellet lot exceeds 98% purity (HPLC area %), confirmed orthogonally: RP-HPLC-DAD (>98.5%, 254 nm), GC-MS (SIM 117/175), ¹H-NMR (δ 1.15 d 3H CH₃, 2.95 m 1H CH, 7.25-7.65 m ArH), HRMS (calcd 176.1070, obs 176.1072). Enantiomeric excess <5% (chiral GC). Residuals: solvents <0.5% (HS-GC), inorganics <50 ppm (ICP-MS), microbes ND (USP <61>). COA details method validation (LOD 0.05%, LOQ 0.1%), system suitability (Rs >2.0, tailing <1.5), and forced degradation (acid/base/oxidative/peroxide stability). Tablets pass USP <711> dissolution and <905> uniformity. Comparative profiling vs. Cayman Chemical 11079 confirms equivalence. Digital COA via lot QR code integrates with ELN/LIMS systems.

Quality Control & Batch Integrity

Pressing employs automated rotary tablet presses with force monitoring (10-20 kN), in-process NIR for API content (RSD <2%). Lot traceability from benzofuran precursor via SAP-ERP to finished packs. Third-party ISO 17025 verification: XRPD polymorphic form I, DSC single endotherm, Raman match score >98%. Retained composites (ICH Q1E) at -80°C for 7 years. cGMP Annex 1 compliant cleanrooms (Grade A); OOS rate <0.1%. Blockchain audit trail logs deviations, CAPA, and change control per 21 CFR 211.188. Homogeneity ANOVA (k=10) CV <1.5%; stability 36 months (40°C/75%RH, ICH Q1A(R2)).

Safety, Handling & Laboratory Precautions

Dissect pellets in Class I fume hoods using stainless dissection tools; avoid pulverizing to minimize dust (inhalation H335). PPE: butyl gloves (>8h breakthrough), P3 respirators, safety gowns. GHS: Acute Tox 4 H302, Skin Irrit 2 H315, Eye Irrit 2 H319, STOT SE 3 H336. Handle as flammable solid (DOT UN1325 PG III). Spill: scoop, HEPA vacuum, wipe with 70% IPA. Segregate from oxidizers. SDS references LD50 >500 mg/kg (est.), LC50 >1 mg/L (rat). Dispose via Schedule 2 incineration (>1200°C). Lab SOPs mandate annual competency via mock exposures.

Packaging, Labeling & Storage

130mg pellets in HDPE bottles (30-100 count) with LDPE liners, child-resistant caps, molecular sieves (3Å). Blister trays optional (Alu-PVC, 10/pack). Labels: GHS diamonds, CAS 286834-84-2, lot/exp, “Lab Reagent – Research Only,” RFID for inventory. Store 15-25°C (<60% RH), 24-month expiry; post-opening desiccate, use <3 months. IATA 4.1 Packing Instr 445; DOT ORM-D if <30 kg. Segregate in secondary containment trays.

Intended Research Use & Market Positioning

Ideal for NPS forensic panels (DEA Schedule I analog studies), tox screening (LC-HRAM-MS libraries), chiral method dev (SFC, Rs>3), and metabolism ID (microsomal incubations). Academic: undergrad synth demos (Grignard benzofuran assembly). Industrial: impurity isolation (>95% prep HPLC). Complements 5-APB/6-MAPB in analog sets; matrix effects quantified for QqQ quantitation (IS 6-APB-d5).

Ordering, Availability & Fulfillment

Stocked for instant WooCommerce dispatch (24h SLA), multi-currency PCI checkout. Ships DHL/FedEx tracked (Tues-Sat), 99% OTP. Bulk (500+) tier pricing; COA rush <4h. Support: live chat, batch lookup portal. DEA exempt (21 CFR 1308.31(g)).​

Legal & Regulatory Disclaimer

This product is sold strictly for research purposes only. Not for human or veterinary use. Not for clinical, diagnostic, or consumptive applications. Buyers assume sole responsibility for compliance with all local, national, and international regulations governing research chemicals. Verify legal status prior to purchase.​