Buy 5-MeO-DMT Powder (Freebase)

Product Overview

5-MeO-DMT Powder (Freebase) offers 5-methoxy-N,N-dimethyltryptamine in its non-salt form, providing a versatile solid organic compound for research settings where control over protonation state, solvent systems, and formulation variables is important. As a synthetic tryptamine, 5-MeO-DMT attracts significant interest for structural, analytical, and physicochemical studies rather than any applied or clinical context in this product format.

This product is supplied as a brandless, ≥98% purity research chemical, suitable for laboratories that require traceable small-molecule inputs for non-clinical investigations, assay development, and reference sample preparation. All use is restricted to controlled laboratory environments under institutional oversight, with no claims or implications regarding suitability for human or veterinary exposure, wellness, or performance-related applications. For research use only. Not for human or veterinary use. Not for clinical, diagnostic, or consumptive applications.

Chemical Identity & Classification

5-MeO-DMT (5-methoxy-N,N-dimethyltryptamine) is an indole-based tryptamine characterized by a methoxy group at the 5-position of the indole ring and a dimethylated ethylamine side chain. In the freebase form, it exists as the neutral tertiary amine rather than a protonated salt, which can influence solubility and volatility relative to its hydrochloride or succinate counterparts.

Key identifiers for the freebase include:

• Chemical name: 5-methoxy-N,N-dimethyltryptamine

• Common abbreviation: 5-MeO-DMT​

• CAS number (freebase): 1019-45-0

• Molecular formula: C13H18N2O

• Molecular weight: approx. 218.3 g/mol​

• Representative synonyms: 2-(5-methoxy-1H-indol-3-yl)-N,N-dimethylethanamine; 5-methoxy DMT.

Within research settings, 5-MeO-DMT freebase is typically classified as:

• A synthetic tryptamine research chemical and small-molecule reference material.

• A tertiary amine, aromatic ether, and tryptamine alkaloid used for non-clinical analytical, structural, and solid-state investigations.

Chemical & Physical Characteristics

Chemical characterizations describe 5-MeO-DMT as a tryptamine alkaloid, aromatic ether, and tertiary amine with a molecular weight around 218.3 g/mol and formula C13H18N2O. In its freebase form, 5-MeO-DMT has been reported as a white solid with a melting point of approximately 69.5 °C, and an experimentally measured water solubility exceeding 32.7 μg/mL.

As a freebase, 5-MeO-DMT shows relatively low overall aqueous solubility compared with many of its salt forms, though it remains compatible with a range of organic solvents commonly used in analytical and preparative chemistry. Its relatively high log P and tertiary amine functionality align with expectations for lipophilic indole derivatives, and formulation work often focuses on salt formation or co‑formulations to adjust solubility and solid-state behavior. Physical appearance for research-grade freebase material is generally described as a solid, which may range from amorphous or semi-solid through to crystalline, depending on processing and storage, with lot-specific details captured in the COA.

Like other indole compounds, freebase 5-MeO-DMT can be sensitive to light, oxygen, and elevated temperatures, factors that are normally managed by limiting exposure, controlling storage conditions, and employing suitable container systems. Such measures help maintain structural integrity and minimize degradation or formation of oxidative byproducts documented in synthetic and stability studies.

Purity & Analytical Verification

5-MeO-DMT Powder (Freebase) is supplied with a purity specification of ≥98%, similar to high-grade research and reference materials used in advanced analytical workflows. This level of purity supports applications in which low-level impurities or residual reagents could affect chromatographic profiles, spectral fingerprints, or quantitative measurements.

In detailed synthetic and characterization work, purified 5-MeO-DMT freebase has been reported with HPLC area purity above 98%, demonstrating that well-controlled processes can deliver high-assay material suitable for downstream salt formation and formulation studies. Identity and purity are typically assessed by a combination of HPLC for assay and impurity quantification, LC‑MS or MS for mass confirmation, and NMR spectroscopy for structural verification, with additional spectroscopic or thermal methods used as appropriate. A batch-specific certificate of analysis summarizing these results and listing key parameters (purity, identity tests, residual solvents, and, where applicable, impurity limits) is usually provided or made available to qualified research customers.

Quality Control & Batch Integrity

Batch-controlled production of 5-MeO-DMT freebase supports traceability from synthesis through packaging, with each lot assigned a unique identifier linking it to full analytical and safety documentation. This structure enables laboratories to track which batch was used in specific experiments, facilitating reproducibility and audit readiness in regulated or quality-managed environments.

In published process development, 5-MeO-DMT freebase manufacturing incorporates in‑process monitoring, targeted removal of dimeric and oxidative impurities, and validated analytical methods to ensure consistent quality of the resulting material. Such workflows include chromatographic clean‑ups, solid-state assessment, and well-defined acceptance criteria, forming the basis of internal QC specifications for reference-grade material. For research customers, this translates into clearly documented lot-to-lot consistency and reliable analytical performance when using the compound as a standard or study analyte.

Safety, Handling & Laboratory Precautions

5-MeO-DMT Powder (Freebase) is intended exclusively for use by trained professionals in appropriately equipped laboratory settings. Standard good laboratory practice should be followed at all times, including the use of appropriate personal protective equipment such as gloves, protective eyewear, and lab coats, and, where required, work within fume hoods or similar containment systems.

Users must consult the substance-specific safety data sheet for detailed hazard and precautionary information, including classification, recommended exposure controls, spill handling, and disposal procedures. Handling protocols should minimize dust generation, uncontrolled release, and contact with incompatible materials, and any waste or residues should be disposed of in line with local regulations and institutional policies. No instructions or implications are provided for dosing, administration, or use in humans or animals; all work must remain within non-clinical, research-only contexts.

Packaging, Labeling & Storage

5-MeO-DMT freebase is typically supplied in sealed research-grade containers designed to protect against moisture, light, and mechanical disturbance during transport and storage. Packaging for reference and research chemicals generally employs robust materials and may incorporate tamper-evident features to allow users to verify product integrity on receipt.

Labeling conventionally includes the chemical name, common abbreviation, CAS number, lot or batch number, and core hazard and precautionary statements compliant with applicable classification systems. Research on 5-MeO-DMT and its salts indicates that storage under cool, dry, and light-protected conditions is important for maintaining stability, with some forms stored refrigerated or frozen depending on formulation and impurity-sensitivity. Laboratories should follow storage and stability guidance from the SDS and COA for the specific batch, and restrict access to authorized, trained personnel only.

Intended Research Use & Market Positioning

5-MeO-DMT Powder (Freebase) is positioned strictly as a research chemical for non-clinical use in professional or institutional laboratories. It may be relevant to analytical chemistry, reference-standard programs, solid-state and salt-screening studies, and basic structure–activity or receptor-binding investigations where such work is legally and institutionally permitted.

The product is not manufactured, licensed, or presented for human or veterinary use, and it is not intended for any clinical, diagnostic, or consumptive application. No claims are made regarding psychological, therapeutic, or performance outcomes, and literature discussing such topics remains separate from the intended purpose of this research-only material. End users are expected to secure any necessary authorizations to handle controlled or scheduled substances if such designations apply to 5-MeO-DMT in their jurisdiction.

Ordering, Availability & Fulfillment

5-MeO-DMT freebase research material is typically distributed through specialized chemical and reference-standard channels to verified institutional and professional buyers. Ordering documentation commonly includes the analyte name, CAS number, lot identifier, and pack details, facilitating accurate internal cataloging and inventory control.

Availability may vary according to production cycles, demand, and regulatory constraints affecting tryptamine-class compounds in different regions. Shipments are usually prepared in robust outer packaging suitable for standard or temperature-controlled logistics as appropriate, with tracked delivery to support chain-of-custody documentation for laboratory receipt. Technical or customer support teams can typically provide COAs, SDS documents, and specification clarification within the strict bounds of non-clinical research guidance.

Legal & Regulatory Disclaimer

This product is supplied strictly as a research chemical for use in laboratory environments by qualified professionals operating under appropriate institutional and regulatory oversight. It is not manufactured, approved, or intended for human or veterinary use and must not be used for clinical, diagnostic, therapeutic, or consumptive applications under any circumstances.

Responsibility for compliance with all applicable local, national, and international laws—including any scheduling, licensing, import/export, and controlled-substance regulations related to 5-MeO-DMT—rests solely with the purchaser and end user. For research use only. Not for human or veterinary use. Not for clinical, diagnostic, or consumptive applications.