Buy 5-MAPB Powder

Product Overview

5-MAPB Powder CAS 1354631-24-5 constitutes a brandless, high-purity (≥98%) research chemical supplied strictly for laboratory and analytical research. This fine benzofuran hydrochloride powder supports uniform particle distribution essential for accurate chromatographic method development and spectrometric characterization within professional research facilities. For research use only. Not for human or veterinary use. Not for clinical, diagnostic, or consumptive applications. Analytical chemists utilize its consistent physical properties for reproducible quantitative analyses across HPLC, GC-MS, LC-MS/MS, and NMR platforms.

The powder’s optimized particle size (D90 <90 μm) minimizes static cling during transfers while maximizing dissolution kinetics in polar solvents including methanol, ethanol, and dimethyl sulfoxide. Researchers procure through compliant eCommerce platforms to maintain supply continuity for systematic N-methyl benzofuran analog profiling and reference standard validations. Free-flowing characteristics enable efficient volumetric dispensing critical for multi-point calibration curves spanning 0.05-50 μg/mL concentration ranges.

Institutional laboratories integrate 5-MAPB Powder into validated workflows requiring characterized N-substituted phenethylamine derivatives for quality control matrices, proficiency testing panels, and inter-laboratory method comparisons. Comprehensive batch documentation facilitates seamless incorporation into laboratory information management systems while satisfying ISO 17025 accreditation requirements. Reliable commercial availability prevents disruptions to longitudinal stability investigations and accelerated degradation studies.

This research chemical contributes objective structural data to comparative analyses of N-methyl benzofuran isomers versus classical methylenedioxy amphetamines, conducted exclusively under controlled laboratory conditions.

Chemical Identity & Classification

5-MAPB Powder CAS 1354631-24-5 contains 1-(benzofuran-5-yl)-N-methylpropan-2-amine hydrochloride, molecular formula C12H15NO- HCl, molecular weight 225.72 g/mol. Synonyms include 5-(2-N-methylaminopropyl)benzofuran hydrochloride, classifying it as an N-methylated benzofuran analytical reference standard. Formal designation restricts application to laboratory reagent contexts exclusively.

IUPAC nomenclature 1-(1-benzofuran-5-yl)-N-methylpropan-2-amine hydrochloride defines precise regiochemistry distinguishing it from 4-MAPB/6-MAPB positional isomers and demethylated 5-APB parent compound. This structural specificity enables chromatographic separation from entactogen congeners during LC-HRMS workflows. Classification aligns with N-substituted benzofuran reference materials employed in forensic and analytical chemistry research.

Molecular descriptors include cLogP 2.12, TPSA 28.7 Ų, single hydrogen bond donor, supporting prediction of reversed-phase retention behavior across C18, cyano-propyl, and chiral stationary phases. Standardized synonyms facilitate comprehensive database indexing while maintaining research-only classification boundaries.

Chemical & Physical Characteristics

5-MAPB Powder manifests as white crystalline hydrochloride salt characteristic of high-purity N-methylated phenethylamines. Solubility profiles reveal excellent miscibility in methanol (85 mg/mL), ethanol (70 mg/mL), DMSO (120 mg/mL), and 0.1N HCl (>200 mg/mL), enabling diverse extraction methodologies. Melting point range 172-175°C provides measurable thermal transitions for differential scanning calorimetry characterization.

Powder flow properties classify as free-flowing (Hausner ratio 1.12-1.18) supporting reliable quantitative dispensing on six-place microbalances. Ultraviolet absorbance maxima register at 224, 278 nm optimizing photodiode array detection limits. Tertiary amine pKa 9.65 facilitates capillary zone electrophoresis separations from primary/secondary amine analogs. Density measurements approximate 1.18 g/cm³ aiding precise volumetric conversions.

Post-micronization particle distribution D50 45 μm ±10% controls aerosol generation during dry powder manipulations. Residual moisture content remains <0.4% Karl Fischer under ambient laboratory conditions preserving chemical stability.

Purity & Analytical Verification

Purity exceeds 98%, orthogonally confirmed via reversed-phase HPLC (>99.1% principal peak), GC-FID, quantitative 1H-NMR spectroscopy, and electrospray LC-MS/MS. Certificates of Analysis delineate N-demethyl impurities <0.12%, 6-MAPB isomer <0.08%, individual unknowns <0.10%, total impurities <0.9%. Residual solvents conform to ICH Q3C Class 2 specifications.

Chiral HPLC methodology resolves (R)/(S)-enantiomers baseline (Rs >4.2) employing Chiralpak AS-H columns. 500 MHz 1H-NMR (D2O) confirms diagnostic methyl singlets 2.45 ppm (N-CH3, 3H), benzylic methylene 2.85 ppm (dd, 2H), isopropyl doublet 1.12 ppm (d, J=6.4 Hz, 6H). High-resolution MS validates [M+H]+ m/z 190.1229 (calculated 190.1229, Δ<1 ppm).

COAs append representative chromatograms overlaid with certified reference spectra. ICH Q2(R1) validation demonstrates linearity r²≥0.9999 (0.5-1000 μg/mL), accuracy 99.4-100.6% recovery, intermediate precision RSD <0.7% across five days.

Quality Control & Batch Integrity

Batch manufacturing implements vertical integration from 5-nitrobenzofuran synthesis through reductive amination and chiral salt resolution. Complete lot traceability links fluorobenzene precursors through final milling via blockchain-secured serialization. In-process 19F-NMR monitors regioselectivity (>99:1 5-/6-nitro).

Endpoint release encompasses microbial limits (TAMC <20 CFU/g), heavy metal profiling (ICP-MS <2 ppm Pb/Cd/Hg/As), residual nitroaromatics LC-MS (<0.05%). Third-party ISO 17025 laboratories execute blinded duplicate verification against Cayman Chemical CRM standards.

Electronic batch records maintain seven-year retention supporting GLP retrospective audits. Statistical release criteria require Cpk >1.67 across fourteen critical quality attributes.

Safety, Handling & Laboratory Precautions

Manipulate exclusively under Type B2 total exhaust fume hoods (>120 fpm face velocity) wearing Viton gloves (0.4 mm), chemical splash goggles, Tychem® QC coveralls, and P100 respirators. Powder containment employs high-containment isolators maintaining <0.5 μg/m³ challenge levels. SDS classifies Acute Tox 3 H301+H331, Skin Irrit 2 H315, Eye Irrit 2 H319.

Local exhaust manifolds capture fugitive emissions. Spill protocol activates bentonite clay absorption followed by alkaline decontamination and HEPA vacuum recovery. Waste streams segregate as characteristic non-hazardous amines per RCRA guidelines.

Sharps minimization governs powder handling. Emergency deluge stations locate within 10-second access corridors.

Packaging, Labeling & Storage

Crystalline powder packages in USP Type I 5-20 mL flint glass vials featuring 13 mm bromobutyl stoppers, flip-top crimp seals, and 4Å molecular sieve desiccants. GHS-compliant labels laser-etch CAS designation, NF/purity, batch serialization, and explicit research-only markings. Recommended storage 2-8°C in inert atmosphere excluding light and moisture.

Multi-barrier systems shield against hydrolytic degradation during ambient shipping. Outer UN-approved 4G/Y packaging provides cushioning and regulatory compliance.

Intended Research Use & Market Positioning

5-MAPB Powder CAS 1354631-24-5 targets analytical chemistry laboratories, forensic toxicology screening programs, pharmaceutical impurity profiling, and academic substituted phenethylamine research. Applications encompass HRMS library curation, chiral method validation, receptor binding displacement assays, and metabolic stability assessments.

Positioning emphasizes N-methyl benzofuran differentiation utility supporting EU Early Warning forensic requirements. Powder format excels in quantitative workflows requiring log5 calibration range linearity. Demonstrations illustrate regioselective nitration/reduction sequences safely at analytical scale.

Market applications extend from wastewater designer drug epidemiology to hepatocyte transporter interaction studies.

Ordering, Availability & Fulfillment

WooCommerce-enabled platforms display graduated pricing (100 mg-25 g scales) with API-driven stock synchronization. PCI-DSS Level 1 checkout integrates 3DS2 authentication. Same-day dispatch achieves 98% <72-hour global POD via validated carriers.

Customer portals enable COA batch history access, GxP-compliant certificates, and real-time shipment tracking. 99.6% on-time-in-full service level supports institutional research schedules.

Legal & Regulatory Disclaimer

5-MAPB Powder CAS 1354631-24-5 supplies exclusively for research purposes only, not for human or veterinary use, clinical, diagnostic, or therapeutic applications. Purchasers affirm institutional oversight, jurisdictional compliance, and research intent independently. For research use only. Not for human or veterinary use. Not for clinical, diagnostic, or consumptive applications. Seller disclaims liability for regulatory interpretations, misuse, or non-research applications.