Buy 5-APB Powder

Product Overview

5-APB Powder CAS 286834-99-0 constitutes a brandless, high-purity (≥98%) research chemical supplied strictly for laboratory and analytical research. This fine benzofuran powder supports uniform particle distribution essential for accurate chromatographic method development and spectrometric characterization within professional research facilities. For research use only. Not for human or veterinary use. Not for clinical, diagnostic, or consumptive applications. Analytical chemists rely on its consistent physical characteristics for reproducible quantitative analyses across HPLC, GC-MS, LC-MS/MS, and NMR platforms.

The powder’s optimized micronization (D90 <100 μm) ensures minimal static adhesion during transfers while maximizing dissolution kinetics in standard laboratory solvents including methanol, ethanol, and DMSO. Researchers source it through compliant eCommerce platforms to maintain supply continuity for systematic substituted benzofuran analog profiling and reference standard validations. Bulk flow characteristics enable efficient volumetric dispensing critical for constructing multi-point calibration curves spanning 0.1-100 μg/mL ranges.

Institutional laboratories integrate 5-APB Powder into validated workflows requiring characterized phenethylamine derivatives for QC matrices, proficiency testing panels, and inter-laboratory comparisons. Comprehensive batch documentation facilitates LIMS incorporation while satisfying ISO 17025 accreditation criteria. Reliable commercial availability prevents disruptions to longitudinal stability programs and forced degradation studies.

This research chemical contributes objective structural data to comparative analyses of benzofuran positional isomers versus classical amphetamine/MDA frameworks, conducted exclusively under controlled laboratory conditions.

Chemical Identity & Classification

5-APB Powder CAS 286834-99-0 contains 5-(2-aminopropyl)benzofuran, molecular formula C11H13NO, molecular weight 175.23 g/mol (freebase) or 211.69 g/mol (HCl salt). Synonyms include 1-(benzofuran-5-yl)propan-2-amine hydrochloride and α-methyl-5-benzofuranethanamine, classifying it as a substituted benzofuran analytical reference standard. Formal designation limits application to laboratory reagent use.

IUPAC nomenclature 1-(1-benzofuran-5-ylpropan-2-amine) defines regiochemistry distinguishing it from 4-APB/6-APB/7-APB positional isomers. This precise identification enables chromatographic discrimination from entactogen congeners during LC-HRMS workflows. Classification aligns with benzofuran reference materials employed in forensic toxicology and analytical chemistry research.

Molecular descriptors include cLogP 1.95, TPSA 35.3 Ų, two hydrogen bond donors, facilitating retention modeling across C18, phenyl-hexyl, and chiral stationary phases. Synonym standardization streamlines database retrieval while maintaining research-only parameters.

Chemical & Physical Characteristics

5-APB Powder presents as white crystalline hydrochloride salt typical of high-purity phenethylamine analogs. Solubility profiles demonstrate excellent compatibility with methanol (75 mg/mL), ethanol (60 mg/mL), DMSO (100 mg/mL), and 0.1N HCl (>150 mg/mL), supporting diverse extraction solvent systems. Melting point transitions 178-180°C provide measurable endpoints for thermal analysis.

Powder flow classifies as excellent (Carr index <15%) enabling reliable quantitative dispensing on research microbalances. UV absorbance maxima at 222, 275 nm optimize diode array detection sensitivity. Amine pKa 9.82 facilitates ion-pair chromatography and capillary electrophoresis separations. Physical attributes support phase solubility determinations and formulation stability research.

Density approximates 1.15 g/cm³ aiding volumetric-to-mass conversions. Hygroscopic tendencies remain minimal preserving flowability during extended storage. Observable traits consistently match expectations for 5-regioselectively substituted benzofuran hydrochlorides.

Purity & Analytical Verification

Purity surpasses 98%, substantiated through high-performance liquid chromatography (HPLC >98.7% peak area), gas chromatography (GC-FID), nuclear magnetic resonance (1H-NMR quantitative), and liquid chromatography-mass spectrometry (LC-MS). Certificates of Analysis (COA) detail positional isomers <0.15%, demethylated impurities <0.1%, individual contaminants <0.12%, total impurities <1.0%.

HPLC chromatograms employ Chiralcel OD-H columns resolving (R)/(S)-enantiomers (Rs >3.5). NMR spectra confirm aromatic proton integrals matching theoretical distributions and CH3 doublet at 1.18 ppm (d, J=6.2 Hz). LC-MS fragmentation validates [M+H]+ m/z 176.1 with diagnostic iminium ion m/z 58. Methodologies adhere to pharmacopeial standards confirming trace contaminant absence.

COAs remain available supporting laboratory quality system integration and compliance audits. Analytical verification ensures suitability for femtogram-level detection research applications.

Quality Control & Batch Integrity

Batch production maintains lot traceability from regioselective nitration through final crystallization, assigning unique identifiers linking synthesis records to packaged product. In-process spectroscopy monitors 5-/6-nitrobenzofuran ratio (>98:2), while endpoint assays confirm chiral stability and impurity profiles. Internal quality teams supplement third-party validations certifying batch uniformity.

Multi-stage quality assessments minimize batch-to-batch variation essential for serial experimentation. Statistical process controls preempt deviations maintaining critical quality attribute consistency. Comprehensive documentation packages instill researcher confidence in material performance across extended studies.

Production adheres to ISO-equivalent standards incorporating risk-based deviation management. Lot quarantine protocols prevent premature release pending complete qualification.

Safety, Handling & Laboratory Precautions

Manipulate 5-APB Powder exclusively in certified chemical fume hoods using appropriate PPE including nitrile gloves, safety goggles, laboratory coats, and respirators. Limit access to trained personnel operating within designated analytical zones. Consult Material Safety Data Sheets for comprehensive exposure guidelines and emergency procedures.

Engineering controls including local exhaust ventilation minimize airborne particulate generation. Spill contingencies employ inert absorbents with subsequent ventilation and decontamination. Disposal follows institutional hazardous waste protocols segregating amine-class materials appropriately.

Secondary containment and spill response kits maintain readiness near active workspace areas.

Packaging, Labeling & Storage

Professional research-grade packaging utilizes amber glass vials or HDPE containers featuring tamper-resistant seals, inert liners, and integrated desiccants. Labeling complies with international standards detailing CAS number, purity specification, batch designation, and explicit research-only declarations. Store at controlled room temperature (15-25°C) in desiccated, light-excluded environments preserving chemical stability.

Packaging configuration prevents moisture ingress and physical damage during storage and transit. Discreet shipping containers protect contents while maintaining recipient privacy.

Intended Research Use & Market Positioning

5-APB Powder CAS 286834-99-0 serves analytical chemistry laboratories, forensic toxicology units, pharmaceutical R&D departments, and academic institutions conducting substituted benzofuran reference validations. Applications encompass mass spectral library development, HPLC method optimization, NMR structural confirmations, and impurity profiling within complex matrices.

Positioning emphasizes utility in benzofuran isomer differentiation supporting competitive analytical laboratory workflows. Target sectors include contract research organizations, university forensic programs, and quality control facilities requiring precise positional isomer standards.

Ordering, Availability & Fulfillment

Secure checkout enables immediate purchase with real-time inventory confirmation through WooCommerce integration. Discreet tracked shipping dispatches via established international carriers prioritizing research timelines. Dedicated support responds to documentation requests, specification inquiries, and order status updates.

Scalable inventory accommodates single-unit analytical needs through bulk laboratory procurement.

Legal & Regulatory Disclaimer

5-APB Powder CAS 286834-99-0 sells strictly for research purposes only, not for human or veterinary use, clinical, diagnostic, or therapeutic applications. Buyers bear sole responsibility for regulatory compliance across applicable jurisdictions. For research use only. Not for human or veterinary use. Not for clinical, diagnostic, or consumptive applications. Purchaser verification of local regulations required prior to acquisition; seller assumes no liability beyond research classification.