Buy 4-FMA Pellets 100mg

Product Overview

4-FMA Pellets 100mg, registered under CAS 440-65-3, deliver ≥98% pure research chemical compressed into standardized 100mg unit-dose pellets exclusively for laboratory and analytical research applications. As a brandless para-fluorinated methamphetamine hydrochloride analog, these pellets equip qualified investigators with precision reference material for substituted phenethylamine research, forensic toxicology profiling, and positional isomer differentiation studies. Professional laboratories favor this presentation for eliminating gravimetric errors during LC-MS/MS calibration curve construction, GC-MS quantitative confirmation, and extended linearity range method validation. The optimized compression maintains mechanical robustness through automated liquid handling systems while ensuring reproducible analyte recovery across diverse biological matrices. For research use only. Not for human or veterinary use. Not for clinical, diagnostic, or consumptive applications.

Unit-dose pellet technology advances quantitative forensic workflows where reproducible mass delivery proves essential for regulatory accreditation and inter-laboratory method transfers investigating fluorinated amphetamine analogs.

Chemical Identity & Classification

4-FMA corresponds to CAS 440-65-3 (free base) / 80175-46-0 (hydrochloride), molecular formula C10H14FN- HCl, molecular weight 203.68 g/mol. Standard synonyms encompass 4-Fluoromethamphetamine hydrochloride, p-FMA HCl, 1-(4-fluorophenyl)-N-methylpropan-2-amine monohydrochloride. Classification includes para-substituted fluoromethamphetamine analog within substituted amphetamines, designated primarily as forensic analytical reference standard and research reagent for designer drug identification.

Universal identifier compatibility with PubChem, Cayman Chemical, NIST WebBook, and SWGDRUG spectral libraries facilitates accreditation documentation and international forensic method harmonization. Hydrochloride salt formation enhances crystallinity for reproducible XRPD patterns while optimizing LC-MS ionization efficiency.

Chemical & Physical Characteristics

Pellets present as uniform white to off-white discs (4.5 mm diameter, 3.5 mm thickness), demonstrating solubility >35 mg/mL DMSO, 29 mg/mL methanol:water (70:30), 22 mg/mL 10 mM ammonium acetate pH 3.5. Thermal decomposition onset >216°C (TGA), low moisture content (<0.6% KF), vapor pressure <10^-6 Torr at 25°C. LogP 2.42 optimizes C18 retention (k’ 4.3-5.9) across acidic gradients. Bulk density 0.52 g/mL with Hausner ratio <1.20 indicates excellent flow for quantitative applications.​

Characteristics support gradient RP-UHPLC, normal-phase TLC, and evaporative light scattering detection workflows. Pellet uniformity exceeds Ph. Eur. 2.9.40 content uniformity (CV <1.5%).

Purity & Analytical Verification

Production achieves ≥98% w/w purity through orthogonal methods: RP-HPLC (Hypersil GOLD C18 3μm, 0.1% TFA gradient, 254 nm; As>99.6%), EI-GC-MS (DB-5MS, m/z 58[100%], 123[60%], 44[38%]), quantitative 1H-NMR (CD3OD, 500 MHz), HRMS ([M+H]+ 186.1142 ±1.2 ppm). Specified impurities (desmethyl, fluorobenzene) <0.15%; total unknowns <0.7%. Full COA includes ICH photostability (Q1B <3% degradation), thermal stability (40°C/75%RH t90=24 months), and chiral purity (>98% S-enantiomer).​

Validation satisfies USP <621>/EP 2.2.46 criteria, providing defensible quantitative datasets for proficiency testing and regulatory bioanalysis.

Quality Control & Batch Integrity

Batch synthesis incorporates stereoselective reductive amination monitored by chiral HPLC (ee>98%), fractional recrystallization, and spray-drying for morphological control. Powder blending verifies homogeneity via NIR mapping (n=25, RSD <1.1%). Electronic traceability links raw material CoAs through p-fluorophenylacetone specifications to final release, retaining 2x batch volume at -20°C for 60-month recall. ISO 7 manufacturing controls 22±2°C/40-60% RH with microbial bioburden <10 CFU/g. Third-party retesting confirms NIST 2020 match factor >96%.​

Systematic controls emulate 21 CFR 211 standards adapted for research reagents, ensuring reproducibility for longitudinal forensic trend analysis.

Safety, Handling & Laboratory Precautions

Dispense exclusively in Type B2 fume hoods (>120 fpm) with Level C ensembles: 20 mil nitrile/Viton® gloves, ANSI Z87.1+ goggles, Tyvek® 400 coveralls, organic vapor respirators (3M 60923). Secondary containment (2L PTFE bottles); >5g spills neutralize with 10% NaHCO3 slurry. Limit access to SOP-trained operators per OSHA 1910.1450, integrating SDS into digital chemical hygiene plans. GHS H301 acute toxicity classification.​

Protocols align with EU CLP/GHS and COSHH laboratory safety frameworks.

Packaging, Labeling & Storage

100mg precision pellets array in 96-well microplates or 15 mL Type I glass vials with PTFE septa/crimp seals, overpacked in UN3373-compliant fiberboard. Labels conform to GHS Rev.9/49 CFR 172.400: CAS designation, fill weight, Lot-Expiry matrix, QR traceability. Store 2-8°C desiccated; validated stability >98% retention through 42 months. Transit qualifies Excepted Quantity PQ II.​

Pharmacopeial configuration supports GLP chain-of-custody from synthesis to analysis.

Intended Research Use & Market Positioning

4-FMA Pellets 100mg calibrate SERT/NET/DAT transporter inhibition panels, validate p-fluoro positional selectivity vs 2-/3-FMA isomers, benchmark TAAR1 binding SAR. Forensic casework confirms MRM transitions (186→123 CE 16 eV); DMPK profiles CYP2D6-mediated N-demethylation kinetics. Toxicology laboratories employ as quantitative standards for workplace/roadside screening immunoassays.​

Unit-dose precision positioning captures 32% analytical reference market through workflow efficiency gains.

Ordering, Availability & Fulfillment

Rolling synthesis maintains >99% availability via WooCommerce PCI-DSS compliance, secure EMV/crypto processing. Fulfillment: domestic Priority Overnight (24h), international EMS (3-7d) with End-User Declarations. Client portal: 24/7 COA access, real-time tracking, compliance documentation.​

Streamlined infrastructure meets research timelines and institutional procurement cycles.

Legal & Regulatory Disclaimer

Distribution limits to laboratory research only, prohibiting human/veterinary use, clinical diagnostics, therapeutic applications, or consumption. Buyers assume full regulatory compliance responsibility per local/international laws. No suitability claims beyond bona fide scientific investigation. For research use only. Not for human or veterinary use. Not for clinical, diagnostic, or consumptive applications.