Buy 3-FEA Powder

Product Overview

3-FEA Powder, identified by CAS 54982-43-3, constitutes ≥98% pure research chemical supplied as fine crystalline powder exclusively for laboratory and analytical research purposes. As a brandless N-ethyl-3-fluoroamphetamine hydrochloride analog, this compound provides qualified investigators with standardized reference material for substituted phenethylamine research, positional isomer differentiation studies, and forensic toxicology method validation. Professional laboratories prefer powder format for quantitative accuracy across microgram-to-milligram dispensing requirements in LC-MS/MS calibration, GC-MS library development, and quantitative impurity profiling workflows. High-purity specification ensures minimal matrix interference critical for trace-level structural confirmation and metabolic profiling investigations. For research use only. Not for human or veterinary use. Not for clinical, diagnostic, or consumptive applications.

This analytical-grade presentation facilitates reproducible integration into diverse solvent systems and automated liquid handling platforms essential for contemporary high-throughput screening and method transfer protocols.

Chemical Identity & Classification

3-FEA registers CAS 54982-43-3 (hydrochloride salt), molecular formula C11H16FN- HCl, molecular weight 217.71 g/mol. Primary synonyms include 3-Fluoroethamphetamine hydrochloride, m-FEA HCl, and N-ethyl-1-(3-fluorophenyl)propan-2-amine monohydrochloride. Classification encompasses meta-substituted ethylamphetamine analogs within the fluoro-phenethylamine series, designated as forensic analytical reference standards and research reagents for designer drug characterization.

Universal database synchronization with PubChem CID 57458869, Cayman Chemical Item No. 23819, and forensic spectral libraries streamlines accreditation documentation and international method harmonization. Hydrochloride salt formation enhances aqueous solubility for LC-MS optimization while maintaining crystalline morphology suitable for solid-state powder X-ray diffraction analysis.

Chemical & Physical Characteristics

3-FEA Powder manifests as white to off-white crystalline solid with D90 particle size <42 μm, exhibiting solubility profiles >34 mg/mL DMSO, 28 mg/mL methanol, 20 mg/mL 0.1% aqueous formic acid (pH 2.8). Thermal decomposition onset >213°C (TGA), residual solvents <1800 ppm (HS-GC), moisture content <0.7% (Karl Fischer). LogP 2.32 optimizes C18 reversed-phase retention (k’ 4.5-6.1), with bulk characteristics including tapped density 0.46 g/mL and Carr’s index <20% supporting quantitative volumetric applications.​

Physical parameters enable robust UHPLC gradient performance, HILIC method development, and 48-hour autosampler stability (>98% recovery). Uniform particle morphology facilitates cryogenic milling for chiral GC separations and ensures representative bulk sampling integrity.

Purity & Analytical Verification

Batches achieve ≥98% w/w purity through orthogonal confirmation: RP-HPLC (Synergi 4 μm Fusion-RP, 10mM NH4OAc/ACN gradient, 254 nm; As>99.6%), EI-GC-MS (Rtx-35MS, m/z 72[100%], 123[52%], 58[42%]), qNMR (CD3OD, 500 MHz), QTOF-HRMS ([M+H]+ 194.1299 ±1.5 ppm). Specified impurities (desethyl, 3-fluorophenylacetone) <0.18% individually; total related substances <1.0%. Comprehensive COA documents ICH Q1B photostability (<4% degradation), thermal excursion tolerance (45°C/4 weeks >97%), and enantiomeric excess (>98% S-form, Chiralcel OD-RH).

Validation satisfies USP <1225>/EP 2.2.46 chromatography requirements, supporting pharmacokinetic bioanalysis and forensic proficiency testing programs.

Quality Control & Batch Integrity

Stereoselective synthesis employs reductive amination of m-fluorophenylacetone monitored by in-process chiral HPLC (ee>98%). Final powder isolation incorporates vacuum drying (45°C/12h) with homogeneity verification via NIR-chemical imaging (RSD <1.2%, n=25). Electronic batch records provide complete traceability from raw material CoAs through crystallization parameters to final release, retaining 2x batch quantum at -25°C for 60-month recall capability. ISO 7 manufacturing suites maintain <40 CFU/m³ airborne contamination with continuous environmental monitoring. Third-party Schedule I laboratories execute blind identity confirmation (NIST 2020 match factor >95%).​

Layered quality controls ensure batch-to-batch equivalence essential for longitudinal toxicokinetic disposition and cross-method validation studies.

Safety, Handling & Laboratory Precautions

Handle exclusively within Type A2/B3 fume hoods (>115 fpm face velocity) using chemical-resistant ensembles: 18 mil SilverShield®/4H® gloves, ANSI Z87.1+ sealed goggles, Tyvek® 400 coveralls, and organic vapor/acid gas cartridges (3M 60923). Secondary containment via 3L HDPE carboys; neutralize >4g spills with 10% ammonium acetate buffer followed by sodium thiosulfate rinse. Restrict access to trained operators per OSHA 29 CFR 1910.1450 Laboratory Standard, integrating batch SDS into digital chemical hygiene platforms. QSAR-derived GHS classification predicts H301+H315+H319 hazard profile.​

Protocols align with EU CLP Regulation 1272/2008 and ANSI/AIHA Z9.5 laboratory ventilation standards.

Packaging, Labeling & Storage

Powder desiccates in 5-50 mL Type I amber glass vials featuring PTFE/silicone septa and crimp seals, overpacked in induction-sealed Mylar® barrier laminates. Labels comply with GHS Rev.9/49 CFR 172.400, specifying CAS designation, Lot-Expiry matrix, UN1849 Limited Quantity exemptions, and 2D DataMatrix serialization. Store at 2-8°C in desiccated explosion-proof units; real-time stability validation confirms >98% assay retention through 40-month expiry. Shipping qualifies as Excepted Quantity PQ II (<30g total).​

Pharmacopeial-grade containment preserves chemical integrity against hydrolytic and oxidative degradation pathways.

Intended Research Use & Market Positioning

3-FEA Powder calibrates monoamine transporter panels (NET/DAT/SERT selectivity ratios), validates N-deethylation metabolic profiling via LC-HRMS, and benchmarks meta-fluoro electronic effects on TAAR1 receptor binding. Forensic laboratories establish differential mobility spectrometry separations from 2-FEA/4-FEA isomers; pharmaceutical DMPK programs quantify plasma protein binding and hepatic intrinsic clearance projections. Toxicology screening employs as certified reference for whole blood confirmation (LLOQ 0.8 ng/mL).

Bulk powder format dominates analytical standards sector through gravimetric versatility advantages over formulated dosage forms.

Ordering, Availability & Fulfillment

Continuous-feed synthesis sustains >99% service levels via WooCommerce PCI-DSSv4 compliance, processing tokenized payments (Visa Token Service), privacy coins, and vetted purchase orders. Fulfillment prioritizes domestic Priority Overnight (24h SLA), international DHL Express (3-7d) with End-User pre-clearance. Client portals provide instant COA downloads, distributed ledger tracking, and automated stability notifications. Framework agreements enable tiered net-30 terms.​

Supply chain architecture accommodates peak academic requisition cycles and forensic laboratory budget timelines.

Legal & Regulatory Disclaimer

Distribution limits strictly to bona fide laboratory research applications, expressly excluding human/veterinary administration, clinical diagnostics, therapeutic deployment, or consumptive utilization. Transferees certify regulatory compliance encompassing 21 USC §813 Federal Analogue provisions, EU NPS Framework 2004/757/JHA, and national analogues. No liability extends to unauthorized applications; mandatory End-Use Statement verification required. For research use only. Not for human or veterinary use. Not for clinical, diagnostic, or consumptive applications.