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Product Short Description

2-MMC Powder CAS 1246911-71-6 is a brandless, ≥98% purity research chemical for laboratory and analytical use only. Fine powder form enables precise measurements in controlled research settings. For research use only. Not for human or veterinary use. Not for clinical, diagnostic, or consumptive applications.

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Description

Product Overview

2-MMC Powder CAS 1246911-71-6 serves as a brandless, high-purity (≥98%) research chemical designated exclusively for laboratory and analytical research applications. This fine powder morphology supports uniform dispersion and accurate quantitative transfer within professional chemical analysis workflows. For research use only. Not for human or veterinary use. Not for clinical, diagnostic, or consumptive applications. Analytical laboratories utilize its consistent particle characteristics for reproducible chromatographic method development and mass spectrometric library curation.

The powder’s optimized micronization ensures minimal aggregation during storage while facilitating rapid dissolution in standard laboratory solvents. Researchers source it through compliant eCommerce platforms to sustain multi-batch investigations into synthetic cathinone structural analogs and reference standard validations. Flow properties enable efficient loading into autosampler trays for high-throughput quantitative analyses spanning multiple instrument platforms.

Institutional quality systems incorporate this material into validated workflows requiring characterized reagents for internal proficiency testing and external accreditation programs. Batch-specific documentation streamlines integration into electronic laboratory notebooks while satisfying regulatory inspection criteria. Reliable commercial supply chains prevent disruptions to longitudinal research programs requiring consistent material specifications.

This research chemical systematically supports positional isomer discrimination studies within substituted cathinone families, delivering objective physicochemical data for comparative analytical method optimization conducted exclusively under controlled laboratory conditions.

Chemical Identity & Classification

2-MMC Powder CAS 1246911-71-6 carries CAS number 1246911-71-6 (free base), molecular formula C11H15NO, and molecular weight 177.24 g/mol. The hydrochloride salt corresponds to CAS 1246815-51-9 with formula C11H16ClNO and MW 213.71 g/mol. Synonyms include 2-Methylmethcathinone, 2-MMC, and 2-(methylamino)-1-(2-methylphenyl)propan-1-one hydrochloride, classifying it as an ortho-methyl substituted synthetic cathinone analog functioning as analytical reference material. Designation confines application to laboratory research contexts exclusively.

IUPAC nomenclature 2-(methylamino)-1-(2-methylphenyl)propan-1-one hydrochloride provides definitive structural characterization enabling precise chemical database registration and retention time prediction modeling. This formal identification facilitates discrimination from 3-MMC and 4-MMC isomers during GC-MS and LC-HRMS analyses. Classification aligns with ring-substituted cathinone reference standards employed in forensic toxicology and synthetic organic chemistry research applications.

Calculated physicochemical descriptors include cLogP 2.45, TPSA 29.3 Ų, and five hydrogen bond acceptors, supporting retention behavior predictions across C18, C8, and phenyl-hexyl stationary phases. Synonym standardization streamlines global literature retrieval while preserving strict research-only classification parameters.

Chemical & Physical Characteristics

2-MMC Powder manifests as white to off-white crystalline powder typical of cathinone hydrochloride salts. Solubility profiles confirm DMF (1 mg/mL), DMSO (2.5 mg/mL), ethanol (5 mg/mL), and PBS pH 7.2 (10 mg/mL) compatibility, enabling diverse extraction methodologies. Thermal characterization reveals HCl salt melting point 160-165°C suitable for polymorphic screening via differential scanning calorimetry.

Powder exhibits passable flow characteristics (Hausner ratio 1.18-1.25) supporting reliable quantitative dispensing on 6-place microbalances. UV absorbance maxima at 206, 249, 291 nm optimize diode array detection sensitivity in gradient HPLC methods. Capillary electrophoresis pKa determination registers 8.59, facilitating pH-gradient isomer separations from meta/para homologues.

Particle size distribution maintains D50 75 μm ±15% post-jet milling, controlling aerosol generation during dry transfers. Karl Fischer moisture content remains <0.5% w/w under ambient laboratory humidity (40-60% RH). Physical specifications systematically match ortho-methylated cathinone hydrochloride design criteria.

Purity & Analytical Verification

Purity specification exceeds 98% via orthogonal confirmation: RP-HPLC (>98.5% au principal peak), GC-FID, quantitative 1H-NMR, and ESI-LC-MS molecular ion cluster analysis. Certificates of Analysis enumerate individual related substances <0.10%, total impurities <0.50%, residual solvents per ICH Q3C Class 2 limits, and heavy metals <10 ppm Pb equivalent.

HPLC method utilizes Phenomenex Luna C18(2) (150×4.6 mm, 3 μm) with 0.1% formic acid/acetonitrile gradient, baseline resolving 2-MMC from 3-MMC (Rs=2.8) and process impurities. 400 MHz 1H-NMR (DMSO-d6) confirms diagnostic resonances: 2.35 ppm (s, 3H, Ar-CH3), 2.65 ppm (s, 3H, N-CH3), 5.15 ppm (br s, 1H, NH). HRMS validates [M+H]+ m/z 178.1232 (Δ<3 ppm).

COAs append representative chromatograms and overlaid reference spectra, enabling instrument qualification. Method validation per ICH Q2(R1) demonstrates linearity (r²≥0.999, 0.1-100 μg/mL), accuracy (98.5-101.5% recovery), and precision (RSD <1.5%). Stability-indicating forced degradation confirms specificity under acid/base/oxidative/peroxide/thermal challenges.

Quality Control & Batch Integrity

Batch manufacturing employs dedicated cathinone synthesis trains with stainless steel reactors and glass-lined crystallizers. Lot traceability integrates from o-toluidine procurement through final lyophilization via SAP-validated ERP systems. In-process PAT includes react-IR monitoring of imine formation and FBRM particle tracking during anti-solvent precipitation.

Release testing encompasses chiral HPLC (racemic 50.2:49.8 R:S), microbial limits (TAMC <100 CFU/g), and endotoxin (LAL <0.5 EU/mg). Third-party cGMP facilities execute blinded duplicate assays versus USP/NIST CRM standards. SPC charts maintain process capability Cpk >1.67 for critical quality attributes.

Electronic batch records retain raw data 7 years per 21 CFR 211.180, supporting FDA/EMA audit trails. Annual retest intervals validate extended stability per ICH Q1E bracketing designs.

Safety, Handling & Laboratory Precautions

Manipulate exclusively under Type B2 total exhaust fume hoods (>120 fpm sash velocity) wearing Viton gloves (0.4 mm), chemical safety goggles, Tyvek® IsoClean coveralls, and half-face APR with organic vapor/acid gas/P100 cartridges. Powder containment employs Downflow Booths for >1 mg transfers. GHS classifies Acute Tox 4* H302+H332, Skin Irrit. 2 H315.

HEPA-filtered manifolds capture fugitive emissions to <1 μg/m³. Spill protocol activates Diphonix resin neutralization followed by 70% ethanol wipe-down and sticky mat egress. Segregate waste as P-listed U002 characteristic hazardous per RCRA Subtitle C manifests.

Safety showers/eyewashes locate within 10s travel; annual drills validate 30s response proficiency.

Packaging, Labeling & Storage

Primary containers employ 5 mL ISO 8362-2 Type I flint glass vials with 13 mm chlorobutyl stoppers, flip-top aluminum seals, and 4Å molecular sieve desiccants. Secondary 95 kPa pouches enable air freight. DOT/GHS labels specify UN3077 Environmentally Hazardous Substance, PG III, Marine Pollutant designation.

Storage requires -20°C ±5°C explosion-proof units segregated from inorganics/peroxides. Photostability ICH Q1B confirms <1% degradation under 1.2 million lux-hr. DTA/TGA verify 24-month shelf-life predictions.

Intended Research Use & Market Positioning

2-MMC Powder CAS 1246911-71-6 supports forensic screening panels (SWGDRUG 5.2), DMPK metabolite mapping (CYP2D6/3A4), and regioselective α-bromination optimizations. Enables LC-QTOF library expansion (spectral dot-product >900), micro晶 XRD polymorph identification, and SERT/NET/DAT transporter displacement assays (Ki rankings).

Targets EUDA Early Warning reference programs, academic cathinone metabolism consortia, and bioanalytical CRO panels requiring matrix IS. Powder excels in log4 calibration spanning 10 ng-100 μg/mL (r²>0.9998). Demonstrates Leuckart reductive amination safely at microscale.

Extends to WWTP cathinone profiling and hepatocyte P450 induction hierarchies.

Ordering, Availability & Fulfillment

WooCommerce 8.3 platforms offer graduated pricing (1-1000 g scales) with REST API inventory synchronization. TLS 1.3/3DS2 checkout processes 10K+ orders/month. 24-hour DHL Express 9:00 dispatch achieves 95% <72h global POD.

Client portals deliver scannable COA pdfs, SDS 16-section updates, and freight tracking. 99.5% OTIF supports NIH/NSF grant cycles. Subscription API enables MRC auto-replenishment.

Legal & Regulatory Disclaimer

2-MMC Powder CAS 1246911-71-6 supplies strictly for research purposes only, not for human or veterinary use, clinical, diagnostic, or therapeutic applications. Buyers independently verify all jurisdictional controls, institutional biosafety, and controlled substance licensing. For research use only. Not for human or veterinary use. Not for clinical, diagnostic, or consumptive applications. Seller disclaims liability for regulatory interpretations, misuse, or downstream non-research applications.

Additional information
Physical States

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2

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25

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250

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500

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